Yale Department of Genetics
@YaleGenetics
Official Twitter home of the Yale University Department of Genetics. Sharing the latest advances in genetics, news and upcoming events.
Could silencing "jumping genes" offer new treatments for Alzheimer's, cancer, and aging? Emerging studies on transposon inhibitors suggest LINE-1 activity may drive neurodegeneration and inflammation. science.org/content/articl…
We're part of this exciting track as well - let's chat if you're interested in developing AI for genetics/genomics (🤖+🧬=💊)!
📢📢 Announcing the Human Genome Sciences track - a brand new addition to the Yale graduate program that aims to train the next generation of scientists in the areas of human genomics, genetics, and bioinformatics. medicine.yale.edu/bbs/tracks/hum…
Researchers with ADHD share how they navigate both the challenges and strengths of their neurodivergence—leveraging intense focus, flexible routines, and self-awareness to thrive in science. nature.com/articles/d4158…
New hope for tough-to-treat childhood cancers: PROTACs—protein-slaying drugs—eliminate, not just inhibit, disease-causing proteins. By hijacking the cell’s disposal system, they target cancers like neuroblastoma once thought undruggable. nature.com/articles/d4158…
Biotech entrepreneur Maya Gosztyla shares how the time-management skills she developed during her PhD now fuel her work in industry—from tracking experiments to balancing fundraising and research. nature.com/articles/d4158…
Academics are often asked to share their expertise “for exposure”—but your time and insights have value. Set clear boundaries, ask about compensation early, and treat your labor as professional. nature.com/articles/d4158…
A new CRISPR system, evoCAST, enables precise, efficient insertion of entire genes into human DNA without cutting it. This is a major step forward in genome editing. Developed through directed evolution, it could transform gene therapies. nature.com/articles/d4158…
Struggling to choose the right postdoc PI? Experts recommend reflecting on your goals, evaluating mentoring styles, asking direct questions during interviews, and speaking with past lab members. Fit matters. nature.com/articles/d4158…
Should you use AI to draft your science job application? Experts say it can be a helpful “thinking partner” for refining goals, translating jargon, and structuring documents—but caution against overreliance. Authenticity still matters. nature.com/articles/d4158…
Stellar flash talk and poster presentation on #ubiquitination regulators in #KRAS inhibitor resistance by our own #CassieMarkham @FASEBorg Protein Phosphorylation! @YaleGenetics @YaleCancer @CancerYale
Workshop: Cancer Cell State Trajectories & Heterogeneity Across Space and Time Cancer cells don’t stay the same—they evolve across tissues & time, adapting to therapy and the microenvironment. But how do we uncover these hidden journeys from noisy, sparse single-cell data? Join…
Proud to present our work at #KCRS25 on CAR-T screens, cell therapy and kidney cancer from @YaleMed @YaleGenetics @YaleWestCampus @YaleCancer Honored to be in session with Drs. Chuck Drake at JnJ, Nadal Rios at Hutch & Patrick Ott at Farber, hosted by David Braun &Hans Hammers.
Neuroscientist Stefano Sandrone shares four practical tips for taking stress-free holidays from academia: release guilt, plan ahead, set and stick to an out-of-office message, and think long-term—because real rest fuels better research. nature.com/articles/d4158…
Researchers have successfully grown the most advanced amniotic sac models to date using stem cells, reaching up to 2 cm in size. This breakthrough offers new insights into early pregnancy and embryo development. nature.com/articles/d4158…
To prepare students for lab emergencies, Colorado State University turned safety training into immersive, theatrical simulations — complete with fake blood, controlled fires, and 911 call drills. A creative model for improving safety culture. nature.com/articles/d4158…
Stressed out by PhD life? Rory Lambe reflects on burnout, resilience, and rediscovering joy during a doctoral journey. From boundary setting to community building, he offers strategies that resonate across disciplines. nature.com/articles/d4158…
🧬 Prime editing—a highly precise CRISPR-based gene-editing tool—has been used in a human for the first time, restoring immune function in a teen with chronic granulomatous disease. A milestone for next-gen genome editing. nature.com/articles/d4158…
#DevBio #Postdocs! Abstracts are being accepted for speakers in the 2025-2026 Ethel Browne Harvey Postdoctoral Seminar Series. SDB postdoctoral members are eligible to apply. Deadline: August 1. #SDBPostdocSeminar bit.ly/3x1ptgb
After receiving the world’s first gene-edited pig kidney transplant, Towana Looney got a message from Timothy Andrews—next in line for the same surgery. Their connection highlights a new era of xenotransplantation, marked by hope and solidarity. science.org/content/articl…
AI-designed antibodies are moving fast. In months, Nabla Bio created dozens that bind tightly to tough targets like GPCRs—some even activate them, opening doors to new therapies. It’s a leap for drug discovery speed and precision. science.org/content/articl…