Richard Voit
@RichardVoit
Pediatric hematology/oncology | Stem cell biology | AML | Gene therapy | CRISPR
Gene therapy is transforming how we treat genetic disorders, but what if mutations in more than 30 genes can cause similar symptoms? Now published in @CellStemCell (cell.com/cell-stem-cell…), we report the development of a universal gene therapy for Diamond Blackfan anemia. 1/n
Inspiring piece in @NatureCancer, "An unexpected career in cancer metabolism," highlights Dr. Ralph DeBerardinis & the pivotal moments that prompted him to pursue a career in cancer metabolism. @CRI_UTSW @HHMINEWS nature.com/articles/s4301…
Catalytic inhibition of KAT6/KAT7 enhances the efficacy and overcomes primary and acquired resistance to Menin inhibitors in MLL leukaemia - by @ShellainaGordon @florian_perner, @Armstrong_dfci, @MAF_Dawson @TheDawsonLab et al. doi.org/10.1158/2159-8… @PeterMacRes @DanaFarber
KAT6A and KAT7 Histone Acetyltransferase Complexes Are Molecular Dependencies and Therapeutic Targets in NUP98-Rearranged Acute Myeloid Leukemia @NMichmerhuizen, Emily Heikamp, @Armstrong_dfci, @CMullighan and colleagues doi.org/10.1158/2159-8… @StJudeResearch @DanaFarber
Be part of the Wagenblast Lab! We are hiring a Lab Manager for leukemia & blood stem cell research at @IcahnMountSinai in NYC, starting July 2025. See ad to apply!
Congratulations @michaelpoeschla and @bloodgenes. Incredible work!
Delighted to have our work on Polygenic Modifiers of #TelomereBiologyDisorders, led by @michaelpoeschla, along with @SashaGusevPosts, @mitchiela, @SharonSavageMD, @hemanth_tummala, and others, published as an advanced online paper in @jclinicalinvest today:…
Excited to share with all our latest work on the use of single cell tools in following IDH mutant AML patients during their treatment! Out today @CellStemCell !! An amazing collaboration with @AkEisfeld & @PapaemmanuilLab & @landau_lab !!! Driven by the impressive @MariaSirenko…
Congratulations Elvin and team. This is a really elegant way to probe an important clinical question underlying aggressive AMLs.
Thrilled to share the first pre-print from our lab! We tackled a big question: Why are some pediatric leukemias extremely aggressive? We explored the developmental origins of fusion-driven acute myeloid leukemia (AML). Let's dive in! #AML #NUP98 n/13
Delighted to have our Perturb-multiome paper, led by @jmartinrufino and #AlexisCaulier from our lab, published today in @ScienceMagazine. Please check out this powerful approach to decipher gene regulatory networks enriched for genetic variation: science.org/doi/10.1126/sc…
Congratulations to @DanaFarber’s Lara Wahlster, MD, PhD, and Nina Weichert-Leahey, MD, for receiving the American Society for Clinical Investigation Emerging-Generation Awards. Read about Dr. Wahlster at bit.ly/4haxdTW and Dr. Weichert-Leahey at bit.ly/4h6BYxL.
Incredibly proud of @tGaoTeng from our lab, who is a recipient of the @HHMINEWS-@DamonRunyon fellowship!!! Congratulations, Teng!! damonrunyon.org/news/entries/8…
I am so excited to be selected as one of the recipients of the Michelson Prize from the Michelson Medical Research Foundation and the @ImmunomePro! This award enables our lab's research at the intersection of systems immunology, virology, and large-scale genomics research.
Congratulations to Dr. Caleb Lareau, 2024 #MichelsonPrizes recipient! His work will study the blood virome and answer the critical question: how do humans have vastly different responses to the same infection?
Congratulations @LWahlster of @DanaFarber who has been named a 2025 Damon Runyon-St. Jude Pediatric Cancer Research Fellow. Read more: bit.ly/42T5TWQ
Gene editing without ex vivo culture evades genotoxicity in human hematopoietic stem cells dlvr.it/THqkNS
Andrew Koh, M.D., @utswpediatrics and @childrens expert, discusses cutting-edge gene therapy treatments for beta thalassemia and sickle cell disease, offering new hope for a cure in children. Learn more: bit.ly/3PBaTYf #PediatricCare #GeneTherapy
Excited to share our new work @ScienceAdvances in collaboration with the Labesse lab. We report the high-resolution Cryo-EM structure of human NADK, revealing a tetrameric organization with distinct structural and functional features. science.org/doi/10.1126/sc…
I am incredibly fortunate to be able to work with this amazing group @hhmi, @BostonChildrens, @DanaFarber, @harvardmed, @broadinstitute!!! 🙏🩸🧬