Peiyu Xu
@Peiyu_Xu_
Excited to share that our latest work on Fanzor is now online in @CellCellPress ! By analyzing structures from different species, we’ve uncovered the structural diversity and how they cut DNA. Huge thanks to Feng @zhangf , Makoto, and all collaborators! cell.com/cell/fulltext/…
Now online! Flexible scaffold-based cheminformatics approach for polypharmacological drug design dlvr.it/T4lzYw
Excited to announce the opening of the Strecker lab at MGH Molecular Biology/CCIB and HMS Genetics. I am tremendously grateful to all of my labmates who have helped me over the years, my past mentors @durocher1 and @zhangf, and my new colleagues @MGHMolBio for the opportunity!
Since the discovery of CRISPR-Cas systems, people have wondered if a similar type of system exists in eukaryotes. Today, we report in @Nature the characterization of Fanzor, a eukaryotic RNA-guided system that can be reprogrammed for human genome editing. nature.com/articles/s4158…
Broad researchers uncover new system in animals that can edit the human genome and may one day be developed into powerful new technology for genome editing. broad.io/Fanzors-news
Thrilled to share my first postdoc paper in @Nature! We present a new RNA-guided system, Fanzor. Heartfelt thanks to @zhangf , Makoto, & team @broadinstitute, and cryo-EM facilities @nyulangone and @mit_nano. nature.com/articles/s4158…
Finally--structures of D1, D2, D3, D4 and D5-dopamine receptors!! Congrats to folks from @RothLabUNC , Eric Xu's lab and many others. nature.com/articles/s4142…
How do LINE family retrotransposons jump around? Can we reprogram retrotransposons? What does this have to do with Rum and Raisin? Answers here and below!
Merging art with AI. Using the new Outpainting capability,DALL-E 2 imagined how the landscape could look like between famous impressionist paintings from Van Gogh, Monet, Munch and Hokusai [source, read more: buff.ly/3F65vrL]
Excited to share our new paper, out today in @Nature! We showed that a PVC (basically a 100nm molecular syringe) can be re-wired to deliver proteins into human cells. Thanks to my advisor, @zhangf, and my amazing co-authors at the @broadinstitute nature.com/articles/s4158…
Structural Genomics of the Human Dopamine Receptor System biorxiv.org/cgi/content/sh… #bioRxiv
Congrats!@ImmunologyTang
Very excited to see my first first-author paper coming out. Thanks to my mentor @Jie_Immunology and our collaborators @ShanLuLiu1 and Cong for powerful help. Particularly thanks to participants in @MayoClinic, also thank @UvaDOM @UVAimmunology for support! (1/5)
Whoo hooo!! Congrats to Shicheng and members of @RothLabUNC and @BShoichet labs for an amazing and thorough interrogation of the structure, function and pharmacology of 5-HT5A receptors! nature.com/articles/s4159…