HoLab
@PCHo_Lab
Scientist grew up in TAIWAN, studied in USA and work in SWISS. Love immunology, cancer and metabolism.
Researchers led by Ludwig @unil’s Ping-Chih Ho, Xiaoyun Li & Sofie Hedlund Møller report that cancer cells secrete fats that prompt fibroblasts to flip macrophages into a pro-cancer state. Disrupting this process impairs growth in melanoma tumors in mice. bit.ly/3U5WYfj
We're recruiting a postdoc to join my lab at @OxfordOncology & Centre for Immuno-Oncology, @UniofOxford to understand immune regulation in cancer and develop new approaches for cancer prevention and metastasis. Deadline: 11 August 2025 Apply here: my.corehr.com/pls/uoxrecruit…
Congrats to my superior student #XiaoyunLi and postdoc @sofie_h_moller and all team members. It was a fun journey to work with mycollaborators in Taiwan and Paris. @Ludwig_Cancer @CancerResearch @unil
Li, Møller, Ho et al. @unil show how tumor-derived lipids can induce an IL-6–dependent increased glutamine synthesis pathway in cancer-associated fibroblasts, supporting CAFs ability to promote pro-tumorigenic tumor-associated macrophages. hubs.la/Q03xvmfr0
Great work from David!!! A must read.
🙏 @manuelansede por el fantástico artículo! 🙏 @annalaura_mstrn & Iñaki Robles-Vera @Teriyaky_852 por liderar el proyecto 🙏coautores que han hecho posible el trabajo 🙏@FundLaCaixa @CaixaResearch principal financiador 🙏 @AgEInves @CienciaGob @ERC_Research apoyo adicional
Congrats to Yoshi’s team. Amazing results!
Microbiota-driven antitumor immunity mediated by dendritic cell migration @Nature nature.com/articles/s4158…
What a amazing 2-photon image from my superb student @Stef_Vil
The May 2025 edition of the Ludwig Link is here! Catch up on the latest from Ludwig researchers, including awards, new leadership and a gallery of beautiful (and fascinating) micrographs. Check it out online here bit.ly/3Fo6LJR or download the PDF bit.ly/3Sq6Uze
A mist read for liver immunologists!
1/ 🚨 Hot off the press in @NatImmunol: CD4⁺ T cells can license Kupffer cells to rescue dysfunctional CD8⁺ T cells in the liver. Hepatitis B virus (HBV) infection is just the proving ground—this is a paradigm shift in tissue immunity. nature.com/articles/s4159… 🧵(1/11) 2/…
🚨 Still a few days left to apply! Our department is looking to host a junior researcher aiming to apply for Ambizione, SNSF Starting Grants (StG), or ERC Starting Grants. Check the conditions here : unil.ch/dof/en/home/me…
Having a great lunch with Alain Fischer, Phil Greenberg, Yu-Huan Tsai and my formal student and future postdoc in Taipei! Go FISS and immunology!
IFN-γ chimeric autoantibody receptor T cells broadly deplete B cells autoreactive against interferon-γ science.org/doi/10.1126/sc… @SciImmunology @KuChengLung
Second paper in a day🫶 Checking out the work of Jhan-Jie Peng, a terrific co-mentored student. CAR T cells against autoantibody producing B cells published in @SciImmunology ! Thanks for the supports from @Ludwig_Cancer @CancerResearch @OncoUNILCHUV . science.org/doi/10.1126/sc…
Check out our new review with my amazing postdoc and formal trainee. A new topic and direction! #tumorimmunology #lymphnode Thanks the support from @Ludwig_Cancer @CancerResearch @OncoUNILCHUV kwnsfk27.r.eu-west-1.awstrack.me/L0/https:%2F%2…
Having a great time in Chicago for AACR 2025. Looking forward to share with everyone another new direction/work we explored in 10 days✌️
It is a great journey from bench to bedside! It is also a fun process to collaborate with my formal trainees, Chin-Hsien and Sheue-Fen. @OncoUNILCHUV @Ludwig_Cancer @CancerResearch
Online now concurrent with the #AACR25 Major Symposium on #Immunometabolism by session speaker @PCHo_Lab: PLT012, a Humanized CD36-Blocking Antibody, Is Effective for Unleashing Anti-Tumor Immunity against Liver Cancer and Liver Metastasis brnw.ch/21wSheD
Joining my talk on Monday in AACR. I gonna present our journey from bench to bedside. Paper will be published simultaneously during my talk. We also just got pre-IND feedback! Let’s help cancer patients with more interventions!!! @Ludwig_Cancer @CancerResearch @OncoUNILCHUV
The AACR Annual Meeting begins today, and we’ve compiled a list of the presentations and posters by Ludwig researchers this year. Consider these excellent additions to your itinerary! #AACR25 bit.ly/4joGR7f
A great piece from @_AnaBelenAg ! Great support from @Ludwig_Cancer @EMBO @CancerResearch
.@_AnaBelenAg & @PCHo_Lab review how aging& diet influence metabolic reprogramming of the tumor–immune microenvironment, contributing to cancer progression & immune evasion as well as strategies to restore antitumor immunity by targeting metabolic pathways hubs.la/Q03g_nzM0
.@_AnaBelenAg & @PCHo_Lab review how aging& diet influence metabolic reprogramming of the tumor–immune microenvironment, contributing to cancer progression & immune evasion as well as strategies to restore antitumor immunity by targeting metabolic pathways hubs.la/Q03g_nzM0
📢 Our department is looking to host a junior research group! We welcome expressions of interest from cancer researchers aiming to apply for funding through Ambizione, SNSF Starting Grants (StG), or ERC Starting Grants. Check the conditions here unil.ch/dof/en/home/me…
iMetAct: An integrated systematic inference of metabolic activity for dissecting tumor metabolic preference and tumor-immune microenvironment dlvr.it/TJP2QP