David Sancho

@SanchoLab

Passionate about #immunology. Sensing damaged self, infections & microbiota by DCs and macrophages to ignite innate & adaptive immunity. #Immunometabolism

Professor @CNIC, Madrid, Spain

Joined September 2019

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David Sancho@SanchoLab · Jul 16

💥 A gut microbe metabolite that drives #atherosclerosis? Yes—Imidazole propionate (ImP) triggers vascular inflammation without changing cholesterol. 🧪 We show the pathway—and how to block it. nature.com/articles/s4158… #OpenAccess at @Nature @CNIC_CARDIO #microbiome #CVD

SanchoLab's tweet card. Nature - Imidazole propionate produced by gut microbiota is associated with atherosclerosis in mouse models and in humans, and causes the development of atherosclerosis through activation of the...

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David Sancho@SanchoLab · Jul 25

🙏 @FundlaCaixa @CaixaResearch for the solid support to our research. This nice blog is about our recent paper on #cDC1s in #atherosclerosis & #immunotherapy ahajournals.org/doi/10.1161/CI… Blog: blog.caixaresearch.org/en/caixaresear… @CNIC_CARDIO

SanchoLab's tweet card. Create, observe, think, correct, rethink… Would you say that these steps form part of the work of an artist, or of scientific research? Of course, it’s difficult to choose without more context. But...

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Carles A. Saura@CarlesSaura · Jul 24

Very good news for European Science: Horizon Europe 2028 - 2034: twice bigger, simpler, faster and more impactful - European Commission research-and-innovation.ec.europa.eu/news/all-resea…

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David Sancho@SanchoLab · Jul 25

Gracias @FundlaCaixa por el sólido apoyo a nuestra investigación. Este reporte en el papel de las cDC1s en la generación de respuesta adaptativa en aterosclerosis @CNIC_CARDIO share.google/fD5kyPv9i7Xmtc… También apoyo fundamental en share.google/NHi2M6tAMxW8Ya…

BBecas Fundación "la Caixa"@BecariosFLC · Jul 25

🔁🎨 Para el #BecariosFundlaCaixa Guillermo Mora, arte y ciencia coinciden en la idea de buscar, ensayar, probar… Hoy nos da su visión artística de una imagen del proyecto @CaixaResearch de @SanchoLab, que busca mejorar la salud cardiovascular.👇 tinyurl.com/3h3cuf5s

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Circulation Research@CircRes · Jul 24

Galán et al found that #cDC1s are proatherogenic via local #immunity & developed a novel #immunotherapy for #atherosclerosis based on cDC1-targeted lipid #nanoparticles. Learn more at ahajrnls.org/3GVqEZy @Sancholab @SBiomagMfb @aramiro_ramiro @CarregalSusana

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nature@Nature · Jul 19

Nature research paper: Imidazole propionate is a driver and therapeutic target in atherosclerosis go.nature.com/4m6m6OZ

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David Sancho@SanchoLab · Jul 19

A gut microbiota metabolite linked to atherosclerosis could revolutionise diagnosis and treatment|ERC erc.europa.eu/news-events/ne…

SanchoLab's tweet card. A new study led by the Spanish National Centre for Cardiovascular Research (CNIC) and funded by the European Reasearch Council (ERC) has identified imidazole propionate (ImP), a metabolite produced...

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Pablo Fuente@PabloFuente · Jul 17

1/12 Revolución en Medicina con Sello Español: Desenmascarado un Nuevo Culpable del Infarto.

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European Research Council (ERC)@ERC_Research · Jul 17

🧬 A new study by @dsancho77 @CNIC_CARDIO links the gut-derived metabolite imidazole propionate (ImP) to #atherosclerosis. The research explores ImP as a potential marker & contributor to early disease development. 👉 europa.eu/!wBktrm #CardiovascularResearch #Cardiology

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Eric Topol@EricTopol · Jul 16

A gut microbiome metabolite promotes atherosclerosis by hijacking the immune system @Nature nature.com/articles/s4158… nature.com/articles/d4158…

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CNIC@CNIC_CARDIO · Jul 18

🎉 🇮🇹 Medios italianos se hacen eco del estudio liderado por @SanchoLab y publicado en @Nature 👉 Rivoluzione nel trattamento dell’aterosclerosi, lo studio su "Nature". Prima autrice la ricercatrice @annalaura_mstrn | @Teriyaky_852 ecoaltomolise.net/rivoluzione-ne… via @EcoAltoMolise

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David Sancho@SanchoLab · Jul 17

🙏 for wonderful summary @manuelansede 🙏 @FundlaCaixa @CaixaResearch for funding (1M€) 🙏 @AgEInves @CienciaGob for Severo Ochoa to initiate the project and additional funding 🙏 @ERC_Research ERC-CoG ERC-POC @CNIC_CARDIO nature.com/articles/s4158…

MManuel Ansede@manuelansede · Jul 17

Revolution in medicine: A molecule produced by gut bacteria causes atherosclerosis, responsible for millions of deaths. The discovery, by @SanchoLab, opens the door to new treatments beyond reducing cholesterol english.elpais.com/health/2025-07…

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David Sancho@SanchoLab · Jul 17

🙏@PabloFuente por fantástico resumen en español. 🙏@FundlaCaixa @CaixaResearch por financiar proyecto con 1 millón € 🙏@CienciaGob por Severo Ochoa que inició el proyecto + 100K€ a nuestro lab 🙏@ERC_Research ERC-CoG ERC-POC @CNIC_CARDIO Open access: nature.com/articles/s4158…

PPablo Fuente@PabloFuente · Jul 17

1/12 Revolución en Medicina con Sello Español: Desenmascarado un Nuevo Culpable del Infarto.

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David Sancho@SanchoLab · Jul 17

Thanks @Borjaibanez1 for the great support on the initial project together 7 years ago & all the way during the development! Looking forward to further work & collaboration with you in this & other projects in future years!!! #cvd #atherosclerosis #cardioimmunology @CNIC_CARDIO

BBorja Ibanez@Borjaibanez1 · Jul 17

This is a landmark in many ways. So proud to have done this with @SanchoLab since time 0. All started with a @CNIC_CARDIO intramural competitive grant part of #SeveroOchoa excellence award to foster basic-clinical partnership. Congrats guys, U R 🔝 @annalaura_mstrn @anadevesa5

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Borja Ibanez@Borjaibanez1 · Jul 17

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