Olivier Borkowski

New on @biorxiv! We’re excited to share our latest paper on combining cell-free systems and machine learning to express full genome in vitro. Check it out ! 👉 biorxiv.org/content/10.110… Catch us at SEED in Houston this June to discuss this work with @LeaWagnerSynBio #CellFree

Research Highlight by @DrArunimaSingh: Self-supervised learning of molecular representations nature.com/articles/s4159…

Plasmids aren't just passengers; they're drivers of bacterial evolution 🧬 Mutation rate scales with plasmid copy number, boosting adaptability 💥 Check out our latest preprint! 🚨 biorxiv.org/content/10.110…

An AI-ready lab notebook for life science doesn't need to be complex or expensive. At @Pioneer__Labs, we use a lab management system built entirely with generic software tools. It's simple, cheap, and easy to modify. See our now how-to post ⬇️

My talk from @bioctrl about the physical origin of agency is uploaded here: youtube.com/watch?v=YY21pH… TLDR: noise equals control. Nature is constantly sampling control trajectories via noise

Ginkgo has launched an E.coli-based Cell Free Protein Synthesis reagent! reagents.ginkgo.bio/products/cell-…

Hydrogel-Immobilized Multienzyme Systems for Cell-Free Chemical Bioproduction pubs.acs.org/doi/10.1021/ac…

🚨 New paper out! In my @NatureSynthesis News & Views, I discuss how light-driven #chemistry enables dynamic life-like #protocells, highlighting the outstanding work of Lin and co-workers #SyntheticBiology #SyntheticCells @imperialcollege @ImperialLifeSci nature.com/articles/s4416…

I am happy to share our pre-print on the genetically encoded control of in vitro DNA replication in the PURE system, including data comparing in vitro system setups and highly active phi29 DNAP mutants. Check it out! A big thank you to everybody @erblabs! t1p.de/e4yhl

Construction and phenotypic classification of synthetic dual-pole Escherichia coli cells "a genetic circuit that enables two distinct scaffolding proteins to localize at opposite poles in E. coli" nature.com/articles/s4200…

🧪 Calling all synthetic biologists! Missed the first deadline? No worries — abstract submissions are now open until 25 July! ⏳ Reviews start Friday, so submit early if you can! 🧬 Register + submit: synbioaustralasia.org #SBA2025 #SynBio

Important work for engineered microbial therapeutics @ScienceMagazine "Controlled colonization of the human gut with a genetically engineered microbial therapeutic" "a therapeutic candidate that reduced hyperoxaluria, a cause of kidney stones" science.org/doi/10.1126/sc…

Localhost is a series of technical talks in NYC given by members of the Recurse Center community. This talk will be the first public glimpse into Mote's motivations, capabilities, and future vision. RSVP via Luma here: lu.ma/cee99o8y

Cell-Free Expression of Nipah Virus Transmembrane Proteins for Proteoliposome Vaccine Design | ACS Nano pubs.acs.org/doi/10.1021/ac…

Online now! A Comment from Paolo Arosio & co-workers covers biomolecular condensates as regulators of enzymatic reactions, with a look at how classical reaction engineering principles continue to provide insights into key underlying mechanisms. Link ($): nature.com/articles/s4428…

Screening and machine-learning assisted prediction of translation-enhancing peptides reducing ribosomal stalling in Escherichia coli doi.org/10.1101/2025.0…

もうIDRバインダーデザイン出たんかいと思ったらまたBaker研だった、つよい Design of intrinsically disordered region binding proteins | Science science.org/doi/10.1126/sc…

Online now: Escherichia coli selection strains for growth-coupled metabolic engineering dlvr.it/TM01f4

Biocircuitry and Living Programmable Materials: The Next Frontier in Synthetic Living Systems pubs.acs.org/doi/10.1021/ac…

🚀 NEW PAPER: Decentralized swarm control without centralized knowledge! We solve the micro-to-macro control problem using only local agent communication. @benia307 @GiancarloMaffet 📄 ieeexplore.ieee.org/document/11045…

Expanding genetic engineering capabilities in Vibrio natriegens with the Vnat Collection doi.org/10.1093/nar/gk…