Michael Mindrum, MD
@MichaelMindrum
Internal Medicine & obesity specialist. Interests in diabetes, behavioral psychology, consciousness, AI. Born in 🇺🇸, 🇨🇦 is home.
Genetically-predicted linoleic acid (an omega-6 PUFA) levels are associated with lower risk of osteoarthritis. In other words, genetic epidemiology agrees with the trials: Swapping out animal fats for seed oils is probably good for this health outcome!
59% of patients with type 2 diabetes in primary care clinics have MASLD, 7% have advanced fibrosis (transient elastography ≥ 10 kPa), and 1.9% have cirrhosis. onlinelibrary.wiley.com/doi/10.1111/jo…
📊 The Obesity Care Cascade 🏥 Where does the breakdown occur in those who have BMI >30 and those who seek a doctor for advice? 🤔 🔻 The largest drop-off (83.7% relative disengagement) occurred between trying to lose weight and seeking professional help 💔 🔻 The second…
One of the most-viewed PNAS articles in the last week is “Energy expenditure and obesity across the economic spectrum.” Explore the article here: ow.ly/utv750WuO3x For more trending articles, visit ow.ly/boza50WuO3q.
Thrilled to finally share what has kept me occupied these past few months; our @TheLancet Series on early-onset type 2 diabetes is out! Has been an honour to be the Lead Author for this Series brining together global experts; thanks @callam_editor for inviting me People…
Casey Means Says Berries Are Going To Make You Fat! Casey means is back on her BS. Honestly, as someone who comes from a conservative household, I am EMBARASSED by the nominations from the republican party, especially Casey Means being nominated as surgeon general because she…
After a couple years of tons of work.. very excited to see that the pre-order for the 5th edition of Biochemical, Physiological and Molecular Aspects of Human Nutrition is live! This 5th Edition has a ton of updates in terms of both content and figures and I think continues to…
Trumpism may consume Trump like a snake eats its own tail.
We do the same! Patients learn to "own their dose" based on the positive effects of satiety (or reduced wanting) or on the other side, negative side effects. I write the script in such a way that the patient can work with their pharmacist over the year to adjust their pen…
We've been slowly uptitrating Ozempic by using "clicks" for a while knowing it would improve tolerability. Great to see we now have data to back this method up!
Just 5 years ago, HFpEF was described as the “stepchild” of HF with no approved therapies. Today, there are 5 US FDA therapies: ✅ Empagliflozin (#EMPEROR) ✅ Dapagliflozin (#DELIVER) ✅ Sotagliflozin (#SOLOISTWHF) ✅ Sacubitril/Valsartan (#PARAGONHF) ✅ Finerenone (#FINEARTSHF)
They learn this from adults! This is about the same % of adults who think its entirely their responsibility according to the ACTION study.
72% of Australian adolescents with obesity believe that weight loss is entirely their responsibility. 72%! This go-it-alone mentality sets the stage for internalized blame. Real obesity care requires a team effort, supporting teens every step of the way. onlinelibrary.wiley.com/doi/10.1111/jp…
MAHA offering a huge victory for sugar sweetened beverages - a health halo that will increase consumption and worsen public health.
What are the relative impact of diet vs physical activity on the global obesity crisis? New paper out @pnas uses the DLW Database with 4000+ participants across 34 populations to investigate Obesity & Energy Expenditure Across the Economic Spectrum. Open access link below!🧵1/
Many moons ago, @KevinH_PhD and I talked about a book we both wished existed. No fads, no weight loss hacks—just the nutrition and metabolism science. I’m thrilled to announce that we wrote it! Out September 23 @Avery_Books & available now for pre-order. penguinrandomhouse.com/books/671334/f…
I’ve been a surgeon for over 30 years… There are many lessons that I’ve learned: Rehab works… more often than you think. Surgery Helps Less Than You Think—But Rehab Helps More After three decades in the operating room, I’ve come to a surprising conclusion—one I wish more…
🎙️ Episode 1 is LIVE! Why is eating well so hard – even when we want to? Neuroscientist @sguyenet breaks down: 🏪 Why our food environment outpaced our biology 🧠 How certain foods hijack our brains 💊 What the data shows about Ozempic & GLP-1 drugs Apple:…
Caloric Restriction Reverses Atherosclerosis, Regain Triggers Progression 1️⃣ Over 60% of people who lose weight regain it, and this weight cycling increases the risk of cardiovascular disease. 2️⃣ This new study investigates how weight loss & regain influence ASCVD, it found…
Today Chat GPT lied to me and I had to debrief with my wife. Such drama.
Very weird interaction with Chat GPT today. It lied to me! Not just a hallucination but straight up lie that seemed to me like it was embarassed or trying to deceive and to use its own words, "save face." So weird. Anyway, this is how it went for the few weird ones that may…