Mike Mitchell

Excited to share our latest in @Nature led by @SwingleKelsey on new mRNA LNP tech to treat life-threatening pregnancy disorders! Kelsey shows that LNPs engineered to deliver mRNA to the placenta can normalize vascular tissue to ameliorate pre-eclampsia: blog.seas.upenn.edu/a-lipid-nanopa…

Escaping the endosome is one of drug delivery’s biggest bottlenecks. The Mitchell Lab @PennEngineers is bending lipids to make mRNA and gene editing therapies more efficient, one nanoparticle at a time. Read more: bit.ly/3EciCJY #GeneTherapy #mRNA #LNP #Bioengineering

How do physical forces shape disease? @Karin_Wang26’s #bioengineering lab @kwanglab at @templebioe is building tissue-mimicking platforms to decode cell behavior and develop new diagnostics. Watch her iTalks video: research.temple.edu/innovation/inn… #TempleResearch

A new video series debuts at the iNest - iTalks features investigators bringing ideas and research to life. From @TempleUniv we are proud to present Dr. Karin Wang and Dr. Philip Dames here: research.temple.edu/innovation/inn… @Karin_Wang26 @kwanglab @templebioe @TempleResearch @TempleEng

Chemical Tweak to Lipid Nanoparticles Cuts Side Effects, Boosts mRNA Potency In multiple experiments, C-a16 lipids, which contain a phenol group, outperformed LNPs used in currently available #mRNA therapeutics @Penn #nanoparticles hubs.li/Q03xVv1Q0

Now accepting applications for Career Awards at the Scientific Interface buff.ly/qobmmjP LOI Deadline: September 2, 2025 #bwfcasi

Fewer side-effects, more effectiveness. @MJMitchell_Lab's lab redesigned mRNA lipid nanoparticles using olive oil-inspired chemistry. Adding phenol groups reduces inflammation, making mRNA therapies safer & more effective. "It's a win-win," says Mitchell.

Thrilled to share our latest in Nature Biomedical Engineering @natBME led by @MJMitchell_Lab Postdocs Ningqiang Gong @DongyoonKim5 on a Mannich reaction approach to create antioxidant lipid nanoparticles for safer and effective mRNA therapy! Free access: rdcu.be/ewN8H

Congrats to Margaret Billingsley on winning the Burroughs Wellcome Fund Career Award at the Scientific Interface! Margaret will pioneer high‑throughput therapeutic nanoparticle platforms to combat ovarian cancer heterogeneity. bwfund.org/news/bwf-annou…

Huge congrats to @MJMitchell_Lab PhD student @ASThatte2 for winning the @Merck best poster award at #CRS2025 for his work on mRNA LNP autoimmune therapies! @CRSScience

Let’s go Coach! @MJMitchell_Lab PhD student and lab softball coach @hannahsafford_ giving a killer talk on lipid nanoparticle elasticity and mRNA delivery to the placenta as part of the Merck Grad Award final presentations at #CRS2025! @CRSScience

NIH will only accept six applications per PI per calendar year. drugmonkey.wordpress.com/2025/07/17/nih… via @drugmonkeyblog

Come check out @MJMitchell_Lab talks this afternoon by Marshall Padilla on LNP biophysics at 535p in Room 119A, @ShiQiangqiang on prodrug LNPs for cancer immunotherapy at 535p in Room 119B, and @hannahyamagata on aromatic mRNA LNP vaccines at 557p in 119B! #CRS2025 @CRSScience

Check out our latest collaborative research article in PNAS @PNASNews with @WeissmanLab and Vlad Muzykantov's labs on cardiotropic lipid nanoparticles for therapeutic siRNA delivery to the heart! pnas.org/doi/10.1073/pn…

Come check out @MJMitchell_Lab talks this morning by @DongyoonKim5 on LNP metabolic reprogramming of dendritic cells for mRNA vaccines at 11:05am in Room 119A and @HannahGeisler_ on targeted LNPs for mRNA delivery to the placenta at 11:27am in Room 124! #CRS2025 @CRSScience

Come check out @MJMitchell_Lab PhD student Emily Han @_emilyhan_’s talk on peptide-functionalized lipid nanoparticles for delivering mRNA across the blood brain barrier today at 11:15am in Room 124! #CRS2025 @CRSScience

From mRNA research to real-world impact—Dr. Swingle is advancing women’s health at @Rice_BIOE. Her work on pregnancy complications like pre-eclampsia began at @PennEngineers. Now, she’s building what’s next in reproductive health—right here at Rice. beblog.seas.upenn.edu

From Penn to @Rice_BIOE, Swingle’s leap from PhD to tenure-track is big and she’s taking women’s health research with her. Her work in mRNA delivery for pregnancy complications like pre-eclampsia began at @PennEngineers. Now she’s building the future. 🔗 bit.ly/44LSYVQ

Kicking off an exciting session at @CRSScience on gene delivery and gene editing with @rvdmnanomeds! Come join the party in Room 119A, @DJSiegwart is on deck! #CRS2025

Come check out @MJMitchell_Lab Postdoc Junchao Xu @Junchao_online’s talk on cardiotropic lipid nanoparticles for mRNA delivery to the heart today at 2PM in Room 119A! #CRS2025 @CRSScience

Nash and Swingle join leadership team at Rice Biotech Launch Pad | Rice News | News and Media Relations | Rice University news.rice.edu/news/2025/nash…