Koch Institute at MIT

What if cancer-fighting cells could think before they act? MIT scientists are programming living cells with logic gates, like tiny biological computers, to detect and destroy cancer with precision. news.mit.edu/2025/equipping…

Save the date for next year’s KI Symposium on Thursday, June 18, 2026! Our theme will be diet & metabolism in cancer. If you were unable to attend this year's symposium or would like to revisit our program, you can now view the videos on YouTube: mit-ki.org/44f6cM3

Congrats to Margaret Billingsley on winning the Burroughs Wellcome Fund Career Award at the Scientific Interface! Margaret will pioneer high‑throughput therapeutic nanoparticle platforms to combat ovarian cancer heterogeneity. bwfund.org/news/bwf-annou…

MIT researchers just unveiled a smarter way to study how treatments interact, potentially accelerating breakthroughs in cancer and genetic disease therapies. news.mit.edu/2025/more-effi…

We’re cell-ebrating the beauty of science! The 2026 Image Awards competition is now open. MIT students, faculty & staff—submit your most striking biomedical visuals for the 15th annual #KIimages exhibition. The deadline is 10/10/25. Details + entry form: ki.mit.edu/imageawards

Congrats to Matthew Vander Heiden (@mvh_lab), Tyler Jacks (@tylerjacksMIT) and Forest White on support from the Stephenson Global Scholar program (@sgpcri). This award will help to drive their bold research in pancreatic cancer. businesswire.com/news/home/2025…

Engineers have created a coin‑sized implant that Daniel Anderson says “is always ready to protect patients from low blood sugar.” It senses low glucose, heats a shape‑memory alloy, and releases glucagon - stabilizing blood sugar within 10 minutes. news.mit.edu/2025/implantab…

MIT and @df_hcc esearchers: The Bridge Project is now accepting proposals for translational cancer research projects. Proposals are due by 10:00AM EDT Tuesday October 14, 2025. For more details: ki.mit.edu/bridge-RFA

Engineers led by 🇺🇸 @kochinstitute / @MIT_IMES and 🇺🇸 @stanford_ee / @StanfordDRC have designed an #implant that could save #diabetes patients from #hypoglycemia. The device can be triggered to release glucagon when blood sugar levels get too low. dlvr.it/TLwVCb

Publication alert 🚨 Mutant p53 hijacks enhancers to drive CXCL1 expression and create an immunosuppressive TME in #PDAC. Targeting these enhancer-chemokine circuits could boost immunotherapy in PDAC. doi.org/10.1016/j.immu… @MGHCancerCenter @kochinstitute @harvardmed

Save the date for next year’s KI Symposium on Thursday, June 18, 2026! Our theme will be diet & metabolism in cancer. If you were unable to attend this year's symposium or would like to revisit our program, you can now view the videos on YouTube: mit-ki.org/44f6cM3

MIT engineers have developed a way to mass-produce drug-loaded nanoparticles that target tumors directly, minimizing side effects and maximizing impact. news.mit.edu/2025/engineers…

Are you an @MIT postdoc in the life sciences? Come join my new initiative, the KendallSqBio Postdoc Symposium on Sept. 10, 2025! ✅ Present your science ✅ Connect with other postdocs ✅ Build your community Abstract deadline July 11th! forms.gle/iXMTYfqgLKWR2E…

Our work on bioelectronic treatment of #brain #cancer has recently been highlighted by @chadtough Defeat DIPG Foundation. Diffuse intrinsic pontine glioma (#DIPG) is a lethal pediatric brain cancer, with no existing cure. Surgery is challenging for DIPG because of the risks of…

Just published in Nature (June 2025), Andersen et al. (@EAChiocca, Reardon, @QuintanaLabHMS) developed a novel viral barcode interaction-tracing (RABID-seq) platform, uncovering previously unknown immunosuppressive interactions between astrocytes and glioblastoma (GBM) cells.…

Don’t miss out on next year’s #KIsymposium!  Mark your calendars for Thursday, June 18 for an exciting discussion of diet and metabolism in cancer. Sign up for our event emails: mit-ki.org/sign-up

That’s a wrap for the day on antibody drug conjugates at the @kochinstitute! Awesome course on these complicated and exciting molecules (and their relatives)! Lots more exciting anti-cancer science to come 💊 #KIsymposium

That’s a wrap on #KISymposium2025—huge thanks to speakers, organizers & attendees! A special shout‑out to our sponsors: @sanofi @AstellasUS, @MilliporeSigma @pfizer, CanCollaborate @QIAGEN @Window_Tx @MoFoLLP @Novartis.

Modifying chemistry of ADCs, such as through adding polar groups to increase lipophilicity is a separate approach that helps improve ADC pharmacokinetics and tolerability @kochinstitute #KIsymposium

Different toxicities can appear with better linkers- indicating a need to better understand the biology of ADCs, as well as improve in other ways to mitigate this toxicity @kochinstitute #KIsymposium