Penn Bioengineering
@pennbioeng
The Department of Bioengineering at the University of Pennsylvania. Established 1973. #PennBioengineering
What if you could control cells with pinpoint precision—no contact needed? @PennEngineers Lukasz Bugaj and team are developing tools to modulate cells remotely using light and heat. See how it could reshape synthetic biology: bit.ly/44MfGPe #Bioengineering #Optogenetics
Escaping the endosome is one of drug delivery’s biggest bottlenecks. The Mitchell Lab @PennEngineers is bending lipids to make mRNA and gene editing therapies more efficient, one nanoparticle at a time. Read more: bit.ly/3EciCJY #GeneTherapy #mRNA #LNP #Bioengineering
Congrats to @PennBioeng’s Dr. Noor Momin—2025 Faculty Starter Grant in Drug Discovery awardee by @PhRMAFoundation! She’s engineering a new, personalized therapy for AFib, one of the most common and disruptive heart conditions, and it’s already advancing toward clinical relevance.
#PhF25 awardee @noor_M0MIN @pennbioeng @PennEngineers is developing a therapy for atrial fibrillation, an irregular heartbeat condition. Her lab found the therapy alleviates #Afib in a mouse model & is now testing in human cells. Watch her full interview: phrmafoundation.org/news-events/bl…
BE’s Prof. Lydon-Staley co-authors new research showing anti-vaping messages tailored to LGBTQIA+ youth are more effective when authentic, specific, and personal. Because without resonance, prevention doesn't reach. 📄 go.nature.com/4nKmEvx @PennEngineers @AnnenbergPenn

Sprouting from research at @pennengineers, @Vivodyne has raised $40M to scale its human tissue platform—a faster, human-relevant alt. to animal testing. Led by @andreigeorgescu (Gr’21), @iamjulieo & Prof. @danhuh_, Vivodyne is pushing biotech forward. 🔗 bit.ly/43IiICa
Not every great idea reaches the people who need it. That’s why a strong pitch deck matters. Dr. Reuther, @PennEngineers, and co-authors share how researchers can translate discoveries into solutions—starting with a clear, credible case for impact. 🔗 go.nature.com/44Z2SUn

Congratulations to Dr. Momin of @PennEngineers on receiving the 2025 @American_Heart Transformational Project Award! Working on a new way to help heart attack survivors avoid heart failure. Seed-funded by CPE4H. 🔗 Read more: bit.ly/4lYaoFZ

From Penn to @Rice_BIOE, Swingle’s leap from PhD to tenure-track is big and she’s taking women’s health research with her. Her work in mRNA delivery for pregnancy complications like pre-eclampsia began at @PennEngineers. Now she’s building the future. 🔗 bit.ly/44LSYVQ

Penn Engineering is proud to announce David Meaney has been named the new Vice Provost for Research at @Penn. An integral faculty member at @pennbioeng, Provost John L. Jackson Jr., states, "[He] is a dynamic and deeply experienced leader, who is engaged with every aspect of…
14 million people worldwide suffer from hypertrophic cardiomyopathy (HCM), an often undiagnosed genetic heart disease. Now, @XueSherryGao (@CBE_Penn & @pennbioeng) and Zheng Sun (@BCMFromtheLabs) are tackling HCM with a $2.5M @NIH grant for a genetic cure.
A fungus once feared as the "pharaoh's curse" has been transformed into a cancer-fighting drug. Led by @XueSherryGao and Qiuyue Nie of @CBE_Penn, researchers turned the toxic Aspergillus flavus into a potent leukemia therapy. Read more: bit.ly/3HX7nqB
The immune system responds like a forest fire unless you control the spark. @raviradhak of @cbe_penn @pennbioeng and @jakebrenner of @pennmedicine decoded how protein spacing flips the immune “on” switch, paving the way for safer nanomedicine. Read more: bit.ly/4eeGVoG
Dr. Michael J. Mitchell has been named the 2025 Kabiller Rising Star in Nanoscience and Nanomedicine. He is recognized for breakthroughs in mRNA delivery using lipid nanoparticles and a polymer "suit of armor" that boosts CAR T cell precision in cancer treatment. @PennEngineers

Meet the 2025 Solomon R. Pollack Award winners from @PennEngineers — four Ph.D. students redefining bioengineering innovation: 🧠 Alzheimer’s 🧬 Cancer drug resistance 👶 Pre-eclampsia 🦴 Cartilage repair Dive into their work: beblog.seas.upenn.edu/2025-pollack-a… #Bioengineering #PhDLife

How do artery cells speed up when blood vessels get stiff? A new study co-authored by @PennEngineers BE’s @SuChinHeo uncovers how the protein survivin helps cells sense stiffness and move—offering clues for future heart disease treatments. 📄 Full study: doi.org/10.1063/5.0252…

Congrats to Dr. Michael J. Mitchell of @PennBioeng on being elected to the @CRSScience College of Fellows! Honored for 10+ years of innovation in drug and gene delivery. 🔗 bit.ly/3SBfCuH #CRSFellow #PennBioengineering #DrugDelivery #GeneTherapy @PennEngineers
Prions are misfolded proteins that can trigger a chain reaction — causing diseases like Creutzfeldt-Jakob. Penn researchers led by @LeeCBassett & @DaniSBassett built a mechanical model that mimics how they spread.
Sepsis can’t wait. Team PRIME’s capillary refill monitoring device helps detect it sooner—and earned 2nd place at the Minnesota Design of Medical Devices Competition. Read how they built it → bit.ly/4mChLUG #SepsisDetection #SeniorDesign #MedTech #PennEngineering

1B+ people need glasses but can’t get an eye exam. Team Prism Optics built a self-guided device to change that—and earned the Leadership Prize at #PennEngineering. Now heading to clinical trials. Read the story → bit.ly/3FBx8ff #vision #GlobalHealth

A brain-computer interface for stroke recovery—designed by undergrads. Team ReFlex earned Judge’s Choice at Penn Engineering’s 2025 competition. Read how their team brought EEG, AI, and FES together in Part 1 of our Senior Design Spotlight: bit.ly/43EnS28 #NeuroTech
