Genetic Engineering & Biotechnology News

Human-Specific Gene Duplications May Hold Clues to Brain Function and Evolution Using data from the T2T reference, scientists linked two new genes to changes in brain size and #synapse signaling @ucdavis #braindevelopment #geneduplication hubs.li/Q03ygbm70

Biogen Plans $2B Manufacturing Expansion at Research Triangle Park Biogen said it intends to invest an additional $2 billion to expand operations at its largest #manufacturing facilities within North Carolina’s Research Triangle Park @biogen hubs.li/Q03ygnlc0

Alzheimer’s Mouse Model Shows Memory Boost from Anticancer Drug Combo Study harnesses a cell-type-specific, multi-target drug discovery strategy grounded in human data and real-world evidence @UCSF @GladstoneInst #drugdiscovery #anticancer #Alzheimers hubs.li/Q03ygbgM0

Novel, Less Toxic, Stem Cell Transplant Prep Yields Successful Outcomes An #antibody treatment successfully prepared patients for stem cell transplants without toxic #chemotherapy or radiation @StanfordMed #stemcelltransplants hubs.li/Q03yg5lt0

Agentic AI Poised to Transform Biomanufacturing This next iteration of #AI is poised to transform #biomanufacturing by overcoming challenges that, today, are insurmountable @soheilmansouri @DTUtweet #AgenticAI hubs.li/Q03y2qX10

About Face: Sarepta to Pause Elevidys Shipments Temporarily Sarepta Therapeutics said it will voluntarily “and temporarily” pause all shipments of the marketed #DMD treatment linked to the deaths of two patients this year @Sarepta #genetherapy #FDA hubs.li/Q03yfQpn0

Don't miss this new eBook! This eBook aims to provide a comprehensive overview of first-void urine as a sample type, highlighting its advantages, challenges, and future prospects. Download this free ebook sponsored by @dnagenotek: hubs.li/Q03vjTJ80

Polygenic Risk Score Predicts Risk of Adult Obesity During Childhood This test can be performed on children before their #geneticrisk starts to shape their weight, which may support early prevention @Metabolcenter @uni_copenhagen #obesity #PGS hubs.li/Q03y2pkK0

FDA Grants Regenerative Medicine Advanced Therapy Designation to Gene Therapy for Osteoarthritis There are no currently available therapies known to alter or slow down the progression of #osteoarthritis @genascence #FDA #genetherapy hubs.li/Q03y2knw0

Transposon Gene Regulatory Roles Revealed Using Phylogenetic Approach A new annotation approach based on cross-species conservation reveals regulatory roles of #transposons in human development @KyotoU_News @Human_Genetics #humangenome #geneexpression hubs.li/Q03y2dwf0

Prime Editing Reverses Childhood Brain Disorder in Mouse Model #Primeediting corrects the most common #geneticmutations that cause alternating hemiplegia of childhood (AHC), a rare and severe #neurological disorder @broadinstitute @jacksonlab hubs.li/Q03y2gKN0

DON'T MISS OUT! On 7/24, Joseph Brealey, an expert in nanoparticle delivery, will discuss current strategies for improving quality control of in vivo CAR T therapies. Register now to join us for this free webinar sponsored by @nano_fcm: hubs.ly/Q03vHRT20

StockWatch: Sarepta Shares Nosedive after LGMD Gene Therapy Patient Dies The death of a third patient tied to a Sarepta Therapeutics gene therapy this year sent the company’s shares nosediving 36% Friday @Sarepta #AAV #genetherapy #FDA hubs.li/Q03y29p20

RNA Expands Its Clinical Clout No longer a mere assistant who carries out the commands of DNA, RNA takes the lead in emerging therapeutics @deepgenomics #AI #RNA hubs.li/Q03xVHhk0

Cell-Free Heart Attack Meds Viewed as Easy-to-Make Alternative to Cell Therapies The concept of using proteins and other secreted factors to treat heart attack, rather than replacement cells, has emerged @TaipeiMedicalU #biomaterials #celltherapies hubs.li/Q03xSjg-0

Getting End-to-End Digital Twins to Work Harder Researchers focus on generating the best possible model from the types of manufacturing data available @SeoulNatlUni #biomanufacturing #biomarkers hubs.li/Q03xS71J0

Miniaturization with Bioreactor Levitation Researchers developed a benchtop bioreactor that can handle mL to liters. Instead of a shaft-driven stirrer, this bioreactor uses levitation. #bioprocessing #bioreactor hubs.li/Q03xMjG50

Consortium Aims to Deliver Fully-Automated Robotics CGT Manufacturing Platform The #CGT sector is currently only capable of #manufacturing sufficient doses to treat less than 7% of eligible patients globally @CellularOrigins @ResolutionTx @CGTCatapult hubs.li/Q03xKlVs0

Agentic AI Poised to Transform Biomanufacturing This next iteration of AI is poised to transform biomanufacturing by overcoming challenges that, today, are insurmountable. #AI #automation #manufacturing hubs.li/Q03xKsmS0

David Baker's Nobel Prize-winning lab at @UWproteindesign has now designed binders to "undruggable" disordered proteins, unlocking therapeutic access to over 50% of the human proteome! Read more at @GENbio: genengnews.com/topics/artific…