LeifLudwig

Thrilled to share 2 reviews from the lab: 🧬 Annual Review Functional Neurogenomics annualreviews.org/content/journa… 🧠 Current Opinion high-throughput analysis of corticogenesis authors.elsevier.com/sd/article/S09… Thanks to my labbies and the field—we were honored to showcase your work! #WeAreHiring

Excited to see BoneMarrowMap out in press! Please check out the R package (now capable of classifying 100,000 hematopoietic cells in 10 minutes) and consider giving the paper a read for some insights into how differentiation goes wrong in AML!

I am a strong believer that depth of data can be just as powerful as scale of data. Deep analysis of small groups of humans, and even individuals, can lead to novel biological insights and principles. Today I am the guinea pig. In my own blood, @CalebLareau finds strong evidence…

Delighted to share an updated review and our perspectives on clonal hematopoiesis and cancer in @NatureCancer in collaboration with Xiurong Cai and Bobby Bowman: rdcu.be/ewN62

🚀 Job opportunity: Bioinformatics Software Engineer Join a young and passionate team at Heidelberg University to advance bioinformatics software that drive biological discovery. Learn more & apply 👉 shorturl.at/GCpg7

🚨 We’re hiring @sangerinstitute! Join us as a Postdoc or ML Scientist to build generative & foundation models for biology. 🧬 Spatial + single-cell omics 🧠 Diffusion, transformers, multimodal data 💊 Drug discovery via Open Targets Apply: Postdocs in computational biology…

In the nucleus, many intrinsically disordered proteins (IDPs) form condensates. What IDP sequence features drive this behavior? We developed CondenSeq, a high-throughput method to measure nuclear condensate formation & applied it to ~14000 IDPs to find out rdcu.be/eq975

What if SCALE is a solved problem? 🤔 Sequencing-Free Single-Cell Genomics with STAMP! 💣 Now published in @CellCellPress: Our approach for scalable, cost-effective analysis of millions of single cells or hundreds of samples—without sequencing. By replacing sequencing with…

Absolutely thrilled to share with you the final version of EPIclone, out now (open access) in @Nature. This has been an amazing collaboration with the lab of Lars Velten (@larsplus) at @CRGenomica nature.com/articles/s4158…

Can AI-designed binders degrade, aggregate, stain and enrich endogenous proteins in human cells? Check out our new preprint! biorxiv.org/content/10.110…

Australia completely lacks a dedicated training program for clinician scientists. With the vision and support of VMIAL @PeterMacCC is extremely proud to announce the first clinician-scientist fellowship. If you meet the eligibility criteria PLEASE APPLY! nature.com/naturecareers/…

We at voitlab.org are grateful to @TexasCCF for supporting our work. Thank you also to @dallascowboys @dak, @Jalen8Tolbert, @tonyromo, @TroyAikman for using their platform to raise awareness and funds for pediatric cancer research. youtu.be/KZwX8Mf7n5I

🎉 Today at #ISCO2025 in Berlin, Andrea Polazzi from our lab shared exciting preliminary results on a novel technology for studying cellular heterogeneity! 🧬 Incredible work, Andrea — we're proud of you! 👏 👉 isco-conference.eu

My lab at @DKFZ in #Germany is looking for #bioinformatician to work on creative solutions for #multiomics #cancer prevention and #DNA #damage mechanisms. #Biologists becoming informatics-proficient - apply here. Deadline approaching. jobs.dkfz.de/en/jobs/167686…

New paper from my lab! Elevated mitochondrial membrane potential is a therapeutic vulnerability in Dnmt3a-mutant clonal hematopoiesis: rdcu.be/eh1Nb Complementary to new work from Steven Chan & George Vassiliou as described by @Goodell_Lab: nature.com/articles/d4158…

Excited to tell you about a new method from our lab, UnitedMet, which imputes metabolite levels/ isotope tracing from RNA data. It features the best first sentence I've ever written: "Comprehensively studying metabolism requires metabolite measurements." nature.com/articles/s4301…

Happy to share our paper describing SPACE-seq - a new approach to spatial multiomics and lineage tracing - out today in @PNASNews! 🧵(1/5) pnas.org/doi/10.1073/pn…

@EMBO workshop on Single cell Lineage Tracing! Sept 18-21 in Sant Feliu, Girona, Spain. Registration is OPEN!!!!! Tons of opportunities for talks are still available (including full length ones). meetings.embo.org/event/25-linea… #EMBOlineagetracing

AND👇🏻the link to our recent article in @NatureCellBio! Treat: 1-We show that human bone marrow hematopoietic stem cells (HSCs) exit quiescence upon myocardial infarction (MI); 2-Our lineage tracing data suggest that HSCs produce pro-inflammatory myeloid.. nature.com/articles/s4155…

Interested in single cell genomics but need help getting started? Check out the full agenda for our Single Cell Genomics Day on Friday 4/25. All talks will be live-streamed (no registration required) at satijalab.org/scgd25