Peggy Goodell

@Goodell_Lab

The Goodell Lab. Hematopoietic stem cells, epigenetics, DNA methylation. Chair, Dept of Mol Cell Biology at Baylor College of Medicine. Tweets my own.

Houston, Texas

Joined March 2012

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Peggy Goodell@Goodell_Lab · Jun 11

So thrilled to have you join the team!

LLudovica Marando, MD, PhD@LudovicaMarando · Jun 11

Thrilled to begin a new chapter at BCM! Alongside developing a CHIP clinic, I will continue research on how CH becomes MDS/AML, and how to stop it! 🙌🏻 Grateful to join the @TXMedCenter community and work with truly inspiring women in science @Goodell_Lab and @TheKingLab

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Jamie Blundell@jrblundell · Jul 3

Delighted to share our latest on longitudinal methylation dynamics preceding cancer. Epigenetic signs of AML appear in blood DECADES before Dx. By brilliant @__AFonseca ✅Early cancer ✅Methylation drivers ✅Epimutation rates ✅CpG lineage tracing biorxiv.org/content/10.110…

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Thomas Rando@Thomas_Rando · Jun 30

Happy to share our recent review as part of the @CellStemCell Hallmarks series, co-authored with friends/colleagues/collaborators, Anne Brunet (@BrunetLab) and Peggy Goodell (@Goodell_lab) Hallmarks of stem cell aging: Cell Stem Cell cell.com/cell-stem-cell…

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Peggy Goodell@Goodell_Lab · Jun 14

So sad to hear of Atul Butte’s passing. ⁦@atulbutte⁩. Fortunate to have briefly crossed paths. To know him for a millisecond was to immediately appreciate his generosity, brilliance, and warmth. He was always thinking, always inspiring. RIP

Goodell_Lab's tweet image. So sad to hear of Atul Butte’s passing. ⁦@atulbutte⁩.

Fortunate to have briefly crossed paths. To know him for a millisecond was to immediately appreciate his generosity, brilliance, and warmth. He was always thinking, always inspiring. RIP

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Elmira Khabusheva@drkhabusheva · Apr 16

Excited to share the @Goodell_Lab News&Views on 3 exciting studies by @VassiliouLab, Chan Lab, and @TrowbridgeLab in @Nature and @NatureComms, showing that blood stem cells with mutant #DNMT3A (major driver of Clonal Hematopoiesis) depend on enhanced mitochondrial respiration ⬇️

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Peggy Goodell@Goodell_Lab · Apr 11

Time-resolved single-cell resolution of cancer development in patients. Deep insights into a leukemia (CML) that has taught the field so much. From an abnormal chromosome (Nowell and Hungerford 1960), to reciprocal translocation (Rowley 1973), to BCR-ABL (Baltimore, Witte,…

JJyoti Nangalia@jyoti_nangalia · Apr 10

The potency of abnormal genetic fusion in chronic myeloid leukaemia in our latest study @Nature 👉🏽 nature.com/articles/s4158… This cancer is an oddity - one of the few single genetic “hit” cancers, a short trajectory (few years) from start to diagnosis, and explosive growth.

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Peggy Goodell@Goodell_Lab · Mar 6

Thrilled to share our work on stem cells and #aging in the hematopoietic system! Lots to dig into, and some interesting parallels and distinctions from human #aging and clonal hematopoiesis.

CChiraag Kapadia@ChiraagKapadia · Mar 6

Delighted to share my PhD thesis work is now published in @Nature! This study tracks the journey of blood stem cells in aging mice, examining how the clonal dynamics of blood production change over time. A short 🧵1/n #aging #stemcells #clonalhematopoiesis nature.com/articles/s4158…

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Jyoti Nangalia@jyoti_nangalia · Mar 5

How blood ages - A curious case of mice and men. Our latest study @Nature published today. Biological processes such as DNA mutagenesis often scale to animal time. Blood stem cells have special evolutionary protection against this. 👉🏽nature.com/articles/s4158…

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Anirban Maitra@Aiims1742 · Jan 13

Cool study on the cover of new @CD_AACR Cancer Prevalence across Vertebrates By @cmaley @amy_boddy Using >16,000 necropsy records across ~300 species, the authors show that neoplasia prevalence (& somewhat more modestly cancer) increases with adult body mass (contrary to Peto’s…

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Peggy Goodell@Goodell_Lab · Dec 8

Was great day to run for the @ASH_hematology foundation run/walk with @TheKingLab @challenlab et al ! #ASH24!

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Taishi Yonezawa@TaishiYonezawa · Dec 7

#ASH24 my poster ready. Hope it leads to CH prevention! Appreciate your fantastic mentorship @Goodell_Lab Would like to thank Dr. Benjamin Ebert and @biomiko for this importan collaboration, For research suport @LLSusa And don't miss @VenkatSundrmrty Goodell Lab talk on Monday!

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Josh Riback@SuperSciJew · Nov 26

🎉 Thrilled to share the @ribacklab’s first PhD defense! Huge congrats to @Gandhar_Datar and co-advisor @Goodell_Lab ! 🎓🔬 Gandhar’s work in biophysics and leukemia led to the discovery of a new phase-separated condensate that drives leukemias. Stay tuned for more insights!

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Peggy Goodell@Goodell_Lab · Oct 31

MCB department tradition! #Halloween party w pumpkin and costume contests. #newPI wins!

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Peggy Goodell@Goodell_Lab · Oct 31

Goodell_Lab tradition! #DNMT3A wins! #TET2 Clonal hematopoiesis!

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AACR@AACR · Oct 28

Submit an abstract by November 18 for the AACR Special Conference on DNA Methylation, Clonal Hematopoiesis, and Cancer (February 1-4, San Diego), chaired by Stephen B. Baylin, Margaret A. Goodell, and Peter A. Jones. bit.ly/48miPFr #AACRmethylation25 @Goodell_Lab

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Peggy Goodell@Goodell_Lab · Oct 22

Great to have Adam Wilkinson @awilkinsongroup visiting the @BCMCancerCenter today hosted by @TheKingLab . Fantastic talk about HSC expansion and exciting genetic in vitro and in vivo screens!

Goodell_Lab's tweet image. Great to have Adam Wilkinson @awilkinsongroup visiting the @BCMCancerCenter today hosted by @TheKingLab . Fantastic talk about HSC expansion and exciting genetic in vitro and in vivo screens!

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Jason Lee@JLeeLab · Oct 18

1/A picture is worth a thousand words but what if they can say more?! We developed live-cell FLIM approaches to track protein interactions within RNA-protein condensates – Our first paper is now out in @JCellBiol! doi.org/10.1083/jcb.20…

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Cancer Discovery@CD_AACR · Oct 10

In the Spotlight: Can ruxolitinib crash TET2- and IDH2-driven clonal hematopoeisis? – by @drkhabusheva and @Goodell_Lab @bcmhouston @BCMFromtheLabs bit.ly/3U6kM2R

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Peggy Goodell@Goodell_Lab · Oct 8

I’m so excited to join this fantastic group of early career scientists! Big shoutout to my @bcmhouston neighbors @HongjieLi5 and @BoeynaemsSteven, my fellow @Planaria1 lab alum @longhua_guo, and my former @stanfordcbio classmate @dianyang1117!

NNIH Common Fund@NIH_CommonFund · Oct 8

Early-stage investigators proposed #innovative high-impact research ideas for the @NIHDirector’s New Innovator Award. See the projects the awardees will pursue: commonfund.nih.gov/newinnovator/A… #NIHHighRisk

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Peggy Goodell@Goodell_Lab · Oct 4

Happy to see the first printed proof of me being a part of @Goodell_Lab. It was a pleasure writing “In the spotlight” on the amazing paper by @RossLevineLab

EElizabeth McKenna@ElizSMcKenna · Oct 4

The October issue of @CD_AACR is online! The cover features features work by @TobyBaker97, @MaxGalder, @VanLooLab and colleagues on the history of chromosomal instability in genome-doubled tumors - read that and much more: aacrjournals.org/cancerdiscover…

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