Chiraag Kapadia
@ChiraagKapadia
Physician-scientist in-training and hyphen-enthusiast interested in hematology, aging, and somatic mosaicism • Clonal hematopoiesis in @Goodell_Lab @BCMHouston
Delighted to share my PhD thesis work is now published in @Nature! This study tracks the journey of blood stem cells in aging mice, examining how the clonal dynamics of blood production change over time. A short 🧵1/n #aging #stemcells #clonalhematopoiesis nature.com/articles/s4158…
🚨 New paper in @NatureGenet ! How does cancer chemotherapy reshape the HSC landscape and drive the evolution of therapy-related myeloid neoplasms? We uncovered this process through single-colony WGS! See the full paper here! nature.com/articles/s4158…
🚨 Our paper is out today in Nature! 🎉🎉🎉 So excited - our paper on the neuronal influence in pancreatic cancer is out in NATURE. You can read here 👇👇👇 (nature.com/articles/s4158…)
Interested in the mysteries surrounding metastasis evolution? This perspective in @NatureRevCancer is my best attempt at proposing a framework that could help advance our thinking about the topic. Well. At least it helped advance my own thinking. 😅 nature.com/articles/s4156…
Excited to share the @Goodell_Lab News&Views on 3 exciting studies by @VassiliouLab, Chan Lab, and @TrowbridgeLab in @Nature and @NatureComms, showing that blood stem cells with mutant #DNMT3A (major driver of Clonal Hematopoiesis) depend on enhanced mitochondrial respiration ⬇️
The potency of abnormal genetic fusion in chronic myeloid leukaemia in our latest study @Nature 👉🏽 nature.com/articles/s4158… This cancer is an oddity - one of the few single genetic “hit” cancers, a short trajectory (few years) from start to diagnosis, and explosive growth.
Thrilled to have the opportunity to train with @BrighamMedRes for internal medicine residency! Can’t wait to move to Boston! #match2025
So excited for this all-star intern crew to join us in June!! Huge congratulations on a fantastic and well-deserved #match2025! 🎉
How blood ages - A curious case of mice and men. Our latest study @Nature published today. Biological processes such as DNA mutagenesis often scale to animal time. Blood stem cells have special evolutionary protection against this. 👉🏽nature.com/articles/s4158…