Duomeng Yang
@DuomengYang
Professor @Jinan University|Former Uconn Health Postdoc-PH Wang Lab|Dept. of Immunology|Innate Immunity
NEW: In tea, onion & celery, the flavonoid apigenin inhibits the NAD-destroying enyzme CD38 & prevents muscle loss in obese rats by upping the anabolic enzyme p70S6K💪 Ozempic adjunct?💉🧵 sciencedirect.com/science/articl…
Researchers are studying why mitochondria are moving between cells and whether the process can be harnessed to treat cancer and other diseases go.nature.com/4jbR6vy
#ChromatinPower #WhatADay! After our paper @ImmunityCP (free👉 authors.elsevier.com/a/1lS0g3qNrU-i…) happy for our tiny contribution to @XuZhouLab @RMedzhitov @younggouu &co amazing paper @CellCellPress showing pH controls inflammation via chromatin remodeling! Free👉 authors.elsevier.com/sd/article/S00…
#EpigeneticPower! Our #NewPaper @ImmunityCP shows that endogenous oxidized lipids decide whether host survives or dies during #sepsis, #ARDS, or Staph infection! Ox lipids bind & inhibit #AKT, boosting inhibitory H3K27 methylation via EZH2, blocking #IL10! authors.elsevier.com/a/1lS0g3qNrU-i…
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Researchers funded by the NIH will be required to make their scientific papers available to read for free as soon as they are published go.nature.com/3Gh7Rr8
#LocationLocationLocation! Nicolas Manel, Xavier Lahaye &co show @CellCellPress that nuclear cGAS senses viruses by recognizing centromeric DNA amplification caused by viral effectors that degrade centromere proteins! cell.com/cell/abstract/…
A 𝐦𝐚𝐜𝐫𝐨𝐩𝐡𝐚𝐠𝐞 is a type of immune cell that plays a crucial role in the immune system by digesting cellular debris and pathogens. Macrophages originate from monocytes in the blood and confer innate immunity, which is typically the body’s first line of defense against…
A healthier brain could one day be just a snort away: bacteria that colonize the nose have been engineered to ferry drugs to the brains of mice. go.nature.com/42NXLa2
When a cancer cell no longer makes a particular functioning protein, it can become dependent on another protein for survival. The identification of one such relationship has uncovered a therapeutic target go.nature.com/3CJftkv
This is like AlphaFold, but for protein localisation rather than folding It's a deep learning model that predicts a protein's subcellular compartment based on its amino acid sequence alone:
Simulations and experiments suggest that an egg is best cooked by repeatedly alternating between boiling and tepid water go.nature.com/4hLepvj
Now we know a major function of #Granzyme K is #extracellular to activate the #complement cascade. Out now @Nature from Carlos Donado and Michael Brenner. @harvardmed @BrighamWomens @Harvard_Imm nature.com/articles/s4158…
We are pleased to announce registration for RNA 2025 - the 30th Annual Meeting of the RNA Society - is now open! www2.rnasociety.org This year’s meeting will be held at the beautiful Town and Country Resort & Convention Center in sunny San Diego, California, USA from May…
New Online! The bystander effect of pyroptosis bit.ly/4jLY4bk
DeepSeek's open AI model is giving scientists worldwide the opportunity to train custom reasoning models designed to solve problems in their disciplines. go.nature.com/40wrDoG
Most human cells in your body do not have DNA / genomes. ~ 90 % do not have DNA. ~ 10 % have DNA
Researchers have shown that patches of muscle grown from stem cells can help to repair a failing heart go.nature.com/3Edodjl
Scientists have tracked microplastics moving through the bodies of mice in real time The tiny plastic particles are gobbled up by immune cells and eventually become lodged in blood vessels in the brain go.nature.com/4h66iJV
Nature research paper: Immune evasion through mitochondrial transfer in the tumour microenvironment go.nature.com/4g81Fhc
Lipopolysaccharide delivery systems in innate immunity dlvr.it/T49vbJ #immunology