Willow Coyote-Maestas

Amazing new work @sookwah_yee @protostasis @Darko_physics between @DelemotteLab, Kathy Giacomini, and my labs! Do you like DMS, protein folding, structure ensemble prediction, Pgx? We used these methods to learn how mutations break a transporter, OCT1. tinyurl.com/OCT1mutant

Happy Sunday to all! This morning, we are excited to share Chase’s work developing a simple, scalable method to assemble 100s-1000s of custom genes from oligo pools using standard lab tools! (Small 🧵 below)

NATIVE BIO is so happy to help with mentorship duties at UW Madison and UC SanFran under the supervision of @willowcoyote and @JudithSimcox @lmclesterdavis WOO HOO! It was a fantastic week.

QBI presents the 3rd Full Circle of Native & Indigenous Scientists in Biology symposium on April 3-4, 2025 at UCSF Mission Bay. A gathering of Native scientists across career stages, focused on community & representation in academia. Join us! qbi.ucsf.edu/full-circle-sy…

Join us on Feb 27 for a seminar with Dr. Janina Sörmann on deep learning’s role in designing modulators for acid-sensing ion channels—a promising yet underexplored stroke therapy target. Hosted by @willowcoyote! Learn more & register: qbi.ucsf.edu/qbi.ucsf.edu/s…

.@UCSF neuroscientist Tomasz Nowakowski, PhD (@LabNowakowski) is leading a collaborative @CIRMnews-funded project using stem cell technologies & #AI to uncover how genetic mutations associated with schizophrenia impact brain development: blog.cirm.ca.gov/2025/02/03/usi… @UCSFstemcell

In the latest issue! Molecular basis of proton sensing by G protein-coupled receptors dlvr.it/THt69x

4/4 Awardee @willowcoyote is unraveling the interactions between genetic mutations🧬 + the environment (ie, exposures like drugs💊 or viruses). His project may transform how we study diseases with complex etiologies. 🎉Congrats Dr. Coyote-Maestas! @UCSF 🙏#HFScout @taekjip

I’m super excited to share what I’ve been working on for the last (many) years: a spatial + genomic + transcriptomic characterization of how the breast cancer microenvironment evolves through immunotherapy! (1/x) biorxiv.org/content/10.110…

Rosace-AA: Enhancing Interpretation of Deep Mutational Scanning Data with Amino Acid Substitution and Position-Specific Insights 1. Rosace-AA is a framework that improves the interpretation of deep mutational scanning (DMS) data by incorporating both position-specific and amino…

Thrilled to share that I was named a Hanna Gray Fellow! It is an honor to join this community with so many of the superstars I admire. Very grateful to @HHMINEWS for their continued support and to my fabulous mentors @AashishManglik, Mark Von Zastrow, and @RachelleGaudet

Welcome all Hanna Gray fellows to the community! We are so fortunate to have you join us. This award and community has changed my trajectory for the better - I can't wait to see all of your research careers blossom!

Congratulations to an amazing postdoc in my group @SashaLFulton on being selected as an HHMI Hannah Gray Fellow! One proud mentor here.

Honored to be named a 2025 @HHMINEWS Hanna Gray Fellow! Grateful to @LaskerKeren for her mentorship and enthusiastic support and to @scrippsresearch for the incredible and inspiring intellectual environment. Excited for the journey ahead! #HannaGrayFellows

Please check out our recent work led by brilliant student @matthewkhoward jointly mentored with @willowcoyote. Willow and I are recruiting joint postdocs!

We are accepting applications for speakers from Native American trainees - if you know of someone who would be a good fit, encourage them to apply here: forms.gle/dMUtGWvigrNAnJ… PS: We have travel funds available! Plz share! More info in the thread.

Super cool science from my colleagues at UCSF- mutational scanning uncovers mechanisms of pH sensing by GPCRs

Tune in for @matthewkhoward’s a tomorrow! Brilliant student from my and @AashishManglik lab working on transformational DMS approaches for gpcrs. Also right on the heels of his first first author paper from our labs!!!