Vince Buffalo
@vsbuffalo
Scientist at IDM. ♥s epidemiology, running, probability+statistics, 🦀, fly fishing, backpacking. Author of book Bioinformatics Data Skills. All views my own.
Yup. I’ve been saying the same thing for months — also wins on memory safety. When LLMs get better at helping write Rust software without using excessive Rc/Arc to get around borrow checker issues, it’ll be even better.
Rust seems poised to be the dominant language in the post-LLM world. Compiler and static typing for deterministic checks against hallucination; native compilation; cross-platform targeting baked in and a package manager that’s a first-class-citizen
I'm thrilled that my lab at NYU is now supported by an NIH MIRA grant! I'm looking to hire 1-2 senior lab members (outstanding postdoc candidates or experienced staff scientists) with expertise in computational and statistical methods in human genetics or genomics. Please share!
Claude Code is getting a brand new feature: custom subagents. Type `/agents` to get started.
Replacing a car with an e-bike can save a household $120,000 over a decade—enough to wipe out debt, fund a college account, or boost retirement savings.
In California's latest housing report shows that in counties like San Francisco, Marin, and Santa Clara, single individuals earning up to $111,700 now qualify for low-income housing programs, per NBC
38 mile ride around Seattle. What a great place to ride bikes. Still can’t believe how long the Burke Gilman trail is, and I didn’t even reach the end!

So stoked to ride the new WA hybrid ferry!
M/V Wentachee heading to Seattle from Bainbridge today. First day back since switching to a hybrid - super cool!
I will miss this. Seattle’s post-9pm summer sunsets are awesome.
We won't have another 9 p.m. sunset until 2026 🌇 king5.com/article/weathe…
Whenever I stumble on Ryan Tibshirani’s PDF notes on a statistical topic I’m learning about, I know I’m in for a treat. Eternally grateful when people host their notes.
I'm very proud to have won the Royal Statistical Society's award for best statistical commentary by a non-journalist this year 🥹 The award was for my piece "The rise in reported US maternal mortality rates is largely due to a change in measurement", which looked at the impact…
Linus used to speak to engineers in 2012 the way I speak to LLMs now.
I deleted my tweet yesterday about @fedex having the worst delivery and customer service, hopeful they would maybe resolve it. Nope, even worse now. Truly the worst operations and customer service I’ve ever experienced. Multiple failures in their software and delivery.
Partner: you should read this fairy book series I like. Me: there’s a book series about ferries?!
Staff scientist position (computational): I am looking for a computational scientist to join my genomics lab at Stanford. They should have an outstanding skillset in ML/statistical methods for genomic applications, postdoc experience and a strong publication record. #sciencejobs
How can we reform science? I have some ideas. But I am not sure you’ll like them, because they don’t promise much. elevanth.org/blog/2025/07/0…