Vijay Iyer PhD

I have been substantially disabled by Long COVID since 2022. Received Pemgarda infusion July 17th, 2025 after reading a few anecdotes of it helping other patients. Also read it did nothing for others. I will be posting my daily progress and answering questions in 🧵 below./1

Very interesting work! Though I would scope the description to what's been found: a neural substrate for prolonged/delayed pain sensitivity. The amygdala & insular cortex have not been so finely mapped or fully understood that projections thereto imply "affective".

Super excited that our landmark @NatureMedicine paper on ME/CFS is out! 🎉 This was years in the making & only made possible because of AI! Big implications for clinical translation, therapeutics. Will do deep-dive thread later today, stay tuned. Grateful to the whole team!🙌

Optimism for science outside of academia is greater than it has ever been in my lifetime...pessimism for science inside academia is also greater than it has ever been. Those who can resolve this tension with out-of-the-box thinking will be astronomically successful.

Tbh the person who responds negatively to a contradiction being pointed out (a pro-cognitive behavior that should be normalized) is the one turning it into a zero-sum game

Neurons are hungry for energy, and carry their own batteries. Excited to share our latest study, on the use of glycogen by neurons as a "capacitors" to support glycolytic plasticity. You can find the article here: pnas.org/doi/10.1073/pn… and press release news.yale.edu/2025/07/15/neu…

Together we go farther. Thanks to a partnership with @ASAP_Research and @MichaelJFoxOrg, the @AllenInstitute's ABC Atlas now includes #ParkinsonsDisease data from 3 million brain cells from 9 regions. This is the first time Parkinson’s data has been included in the Atlas. It…

While I disagreed with how Dr. Ladapo spoke exclusively to vaccine-triggered conditions during the pandemic, I welcome his broader view here. #longvax is too big a clue* to lose to taboo! (and vice versa) *into #longcovid

It is great that you're posting - the more attention the better. I have multiple friends whose lives have been dramatically altered by this. My hope is #LongCovid as brought much needed attention to #MECFS. I'm sure that the mechanisms are general and behind many illnesses.

Sadly, I am no longer a professor at ETH (@eth_en) due to very severe #longCovid and #MECFS. ethrat.ch/de/ernennungen….

While I see lots of good things from #neuroimaging (with human MRI etc), it's also clear to me much of public & medicine doesn't know how far micro-scale #neuroscience has come (which is mostly animal)

Here is my takeaway from interacting with my friends and colleagues - some of the best autonomic specialists in the world - and discussing #POTS/#Dysautonomia at #DysConf2025 this past weekend: 🧠 You've got to be open-minded regarding the complexities of these disorders.…

The impossible happened. I recovered from bedbound, to housebound, and now I'd consider myself mild on the #longcovid #mecfs spectrum. I'm well enough to go to school; in fact, I just completed my first year at Stanford business school.

Good points, though it has to be more than the 'reach of care'. Longitudinal tracking could become a major new 'source of discovery'.

What if we could quantify RNA synthesis directly? My colleague @DigbijayMahat has recently achieved this feat at single-cell efficiencies using click chemistry. These datasets quantify changes within minutes! nature.com/articles/s4158… 4/5

Same with "stress". Lewis Thomas pushed back on demonization of stress back in the 70s & 80s with a quote to effect of "stress is life". I'm trying to relocate source of this spot-on point.

Read your paper when it came out and I agree 100%. I would argue that animal models (not only mice) are still irreplaceable in certain scenarios, e.g. neural and neuroimmune circuit manipulations, where interesting biology arises beyond the level of cell or organ.