Dr. Shelby
@shelbynewsad
Imbibing science 24/7. Partner @compoundVC | Writing http://shelbyann.substack.com | Bio PhD @cambridge_uni | @OhioState Biochem
(New Playbook) Human evidence is everything in biotech. It’s the proof that a new therapeutic works, the foundation for investor belief, and the floodgate for real-world patient impact. This is why us @CompoundVC have written a playbook on how biotech companies can get human…

This is beyond important. We’re seeing that Biotech is the next big frontier but many companies just have a concept and maybe early lab data. @CompoundVC outlining a human evidence playbook is great.
(New Playbook) Human evidence is everything in biotech. It’s the proof that a new therapeutic works, the foundation for investor belief, and the floodgate for real-world patient impact. This is why us @CompoundVC have written a playbook on how biotech companies can get human…
Give us human evidence or give us death
We have the technology, we just need the will.
This is true. Please reach out if you want to chat human challenge trials.
They’re massively important. @mhdempsey on my team is obsessed if you ever want to chat about HCTs with us.
Come chat to us about platform <> human evidence fit
Thank you! I learned a few new options from this as we get close to our IND, appreciate it
Completely agree - as clinicians we almost exclusively look at human clinical evidence. If we could enable human phenotypic screening, it would allow biotech to iterate at tech speed, and medicine would accelerate a few hundred years into the future
nice, this is great! many people underestimate these bottlenecks, and for biotech as for many other fields, AI will only increase the importance of speeding these parts of the process up
biotech companies need to get human data as quickly as possible and there are many underdiscussed avenues for doing so. Highly recommend reading our latest from @shelbynewsad
(New Playbook) Human evidence is everything in biotech. It’s the proof that a new therapeutic works, the foundation for investor belief, and the floodgate for real-world patient impact. This is why us @CompoundVC have written a playbook on how biotech companies can get human…
This is the era where sci-fi comes to real life
Kind of crazy that humans learned to assemble the molecular motors designed by evolution
Compound is a forecasting firm.
Us @CompoundVC put pen to paper last year on predicting the next five years of biotech, AI and Bio, and societal shifts through the lens of biohacking. We were right on 10 of our biggest forecasts: >Bryan Johnson launches a Netflix documentary - Yes >Public supplement…
Cloud cities on Venus - a very well-researched idea by @ThatMrE
No - let's live in cloud cities. A lot easier: thatmre.medium.com/we-re-going-th…
Bring back cell free catalysis for SAF ⚡️
solugen style cell-free electro-enzymatic CO2 to hydrocarbon chain products like SAF at an economics better than crude oil..
Convergent ideas - cancer gladiators fighting cancer on cancer
Amazing. My co-founder (linkedin.com/in/tatyana-dob…) pitched this to our PI in grad school. In case y'all want to talk =p She called it "cancer gladiators"
Non-model organisms for life on Venus
Ok. How do we get started? We can reconfigure our programmable biosphere device but needs some upgrades for Venus conditions. @CultivariumFRO
New modes of measurement enable new understanding
Light-up nanostructures with allosteric DNA mimics of GFP doi.org/10.1101/2025.0…