Oriol Pich
@oriol_pich
MD, postdoc at @SwantonLab, previously @bbglab 🎸
🚨Thrilled to share our latest work: “Tumor-Infiltrating Clonal Hematopoiesis” @NEJM - we investigated how age-related blood mutations impact cancer when they infiltrate tumors, with @Elsa2Bernard Maria Zagorulya, @PapaemmanuilLab @CharlesSwanton + more nejm.org/doi/full/10.10…
New PI alert! They are lucky to have you will - can't wait to see what you are going to do next!
Thrilled to announce I'm moving to the @CRUK_MI to lead the Cancer Origins group! If you're interested in how mutations and exposures drive tumourigenesis—come join the adventure. cruk.manchester.ac.uk/careers/
CHIP is a common, age-related condition where mutated blood stem cells expand without causing blood disorders. CHIP raises the risk of hematological malignancies, chronic inflammatory diseases (like heart & lung disease), & lung cancer. This manuscript shows that CHIP somatic…
I enjoyed reading/learning about TI-CH paper in @NEJM =>Tumor-Infiltrating Clonal Hematopoiesis | Work from @oriol_pich @Elsa2Bernard @PapaemmanuilLab, @CharlesSwanton + team! Editorial by @DanaFarber Ebert/Weeks nejm.org/doi/full/10.10…
🚨So proud to present the first study from our @CCG_UCL group together with @CharlesSwanton @NnennayaKanu and led by @ojlucas with key collaboration @Ward__Sophie and fundamental support @Rija_Zaidi_ @abi_bunkum & many others Out in @NatureGenet 👇 doi.org/10.1038/s41588… 🧵👇
How prevalent is ecDNA in tumours? Do they always contain oncogenes? What is their clinical impact? Check out our latest paper @Nature to find out! So proud of the team—especially superstar Chris! To more adventures together 👹🎸 nature.com/articles/s4158…
Hot off the press!! 🔥 Check out our work on the origins and impact of ecDNA. This was a team effort involving multiple collaborators as one of a three part series on ecDNA in @Nature
Together with @CharlesSwanton, delighted to share that our new tool, MHC Hammer - which can detect different types of HLA disruption - mutation, loss, RNA repression and alt. splicing - is now out in #NatureGenetics and available to use…nature.com/articles/s4158…... 🧵below
🎉New paper🎉Introducing #StrandInteractions, the sequel to #LesionSegregation, published today @Nature Strand-resolved mutagenicity of DNA damage and repair nature.com/articles/s4158… Here’s what we discovered about (a)symmetry in replication, transcription & #mutagenicNER [1/13]
Incredibly honoured that our work has been recognised! Our work is computational, focussing on using data to understand cancer - we are entirely reliant on wonderful collaborators and public data. (& generous funders @wellcometrust @CRUKCOLcentre @CRUKLungCentre @RosetreesT)
🎉The Blavatnik Awards and @nyasciences are excited to announce the Honourees of the 2024 Blavatnik Awards in the UK! Please join us in congratulating these nine incredible scientists sparking innovations that will transform our future world. Learn more: blavatnikawards.org/news/items/pre…