Mile Sikic
@msikic
Group leader @astar_gis, Prof @SveucilisteZG, partner @OraclumCapital. AI in Genomics
Our RiNALMo RNA language model has been published in Nat Comm nature.com/articles/s4146… Great work by @RJPenic and @TinVlasic, with support and patience in teaching us RNA biology from Roland G Huber and @ywan_wan RiNALMo is already an SOTA as a benchmark for RNA LLMs.
Singapore RNA Seminar Series🧬 Join us at our next seminar by Dr. Kate Chiappinelli, Associate Professor of Microbiology, Immunology, & Tropical Medicine, The George Washington University on 19 Aug 2025, 9:00AM (SGT, GMT+8). Host: Associate Professor Polly Chen, NUS Link:…
🎓PhD Opportunity: AI x Genomics at A*STAR Genome Institute of Singapore (A*STAR GIS) 🧬🤖 Are you passionate about pushing the boundaries of science with cutting-edge technology? Join us for a transformative PhD journey at the intersection of Artificial Intelligence and…
Seeking potential PhD students - Developing novel RNA therapeutics using AI-driven approaches - Decoding cancer genomics using LLMs and GNNs Deadline 1/6/2025. Contact me directly! a-star.edu.sg/Scholarships/f…
Are you worried about your DNA revealing too much about you? The @washingtonpost says you should be very worried. I have a different take: stevensalzberg.substack.com/p/i-know-genom…
Happy to present the first complete genome of an Indian individual biorxiv.org/content/10.110…. Joint effort by @astar_gis ,FER, and partners, with support from the Singapore NPM programme! Joint effort with JJ Liu Lab! @msprasad693 and @JosipaLipovac as co-first authors.
I am happy to introduce Campolina, a deep neural framework that replaces traditional algorithmic approaches for nanopore signal segmentation and improves segmentation quality for real-time analysis. Preprint and details in the thread👇 K. Friganovic, @BryanHooi1, @msikic 1/7
🎉Calling All Scientists, Clinicians and Innovators! 🎉 Join us as we celebrate 25 years of genomic excellence at the #GIS25: Genome Innovation & Precision Medicine Conference, happening 11–12 September 2025 at Matrix Auditorium, Biopolis, Singapore! 🔬 Dive into the future of…
🧵1/n Estimating mutation rates using k-mers is fast—but what happens when repeats dominate the genome? In a new preprint, @HaonanWu_1998, Antonio Blanca, and myself propose a *repeat-aware* estimator that's accurate even in centromeres.
A k-mer-based estimator of the substitution rate between repetitive sequences biorxiv.org/content/10.110… #biorxiv_bioinfo
GW: ultra-fast chromosome-scale visualization of genomics data. #GenomeVisualization #Bioinformatics #Genomics @naturemethods nature.com/articles/s4159…
Preprint on "Improving spliced alignment by modeling splice sites with deep learning". It describes minisplice for modeling splice signals. Minimap2 and miniprot now optionally use the predicted scores to improve spliced alignment. arxiv.org/abs/2506.12986
As a genomics person, I couldn't think of a better place in Asia to work than the Genome Institute of Singapore. We are recruiting for RNA, AI and Precision health. If interested Principal Investigator, GIS job with Agency for Science, Technology and Research (A*STAR) | 673811
Slides from my talk (with Kamil Jaron) on an history of k-mers in bioinformatics: rayan.chikhi.name/pdf/2025-kmers…
We observed that tRNA genes mutate like no tomorrow 👇
In this fascinating preprint, the authors uncover an eye-opening feature of tRNA genes: they’re insanely prone to mutation. Analyzing somatic mutations in cancer tissues, they report that tRNA genes are up to 9 times more mutated than protein-coding genes. Interestingly, the…
1/4 Hash functions in genomic sequence analysis (tinyurl.com/4kk9ccmt) : a new survey written together with @shaomingfu, @kanatos92, @xianglipsu, and Qian Shi. Before submitting it, we are posting it online to get feedback from the community.
The further a scientist moves away from the topic of their previous work, the fewer citations their new work will receive, according to an analysis of millions of scientific papers and patents published in @Nature. go.nature.com/3HdyflX
📢 Introducing Biomni - the first general-purpose biomedical AI agent. Biomni is built on the first unified environment for biomedical agent with 150 tools, 59 databases, and 106 software packages and a generalist agent design with retrieval, planning, and code as action. This…
25 years? No way. The Genome Institute of Singapore is all grown up now! How time flies. Join us 11-12 September to celebrate our landmark birthday. Stellar lineup of Genomics and Precision Medicine speakers from across the globe! #GIS25 @astar_gis
🎉GIS turns 25! Join us in celebrating 25 years of innovation at #GIS25: Genome Innovation and Precision Medicine Conference, happening 11–12 September at Matrix, Biopolis, Singapore! 🌍This milestone event will bring together global leaders in genomics research who will share…
New metagenome assembler for @Nanopore R10 and @PacBio HiFi reads from Jim Shaw
Announcing myloasm, a new long-read (ONT R10/PacBio) metagenome assembler. With @lh3lh3. myloasm-docs.github.io
🎉GIS turns 25! Join us in celebrating 25 years of innovation at #GIS25: Genome Innovation and Precision Medicine Conference, happening 11–12 September at Matrix, Biopolis, Singapore! 🌍This milestone event will bring together global leaders in genomics research who will share…
Folks, a historic first @humancellatlas General Meeting in Singapore - the place where single cells meet their match! Late bird registration never closes. But the meeting starts on June 9, so that’s your final deadline … See you at #HCA2025GM
We are excited to feature keynote talks from Soumya Raychaudhuri @soumya_boston and Ge Gao @gao_laboratory at the #HCA2025GM