Mohamad Amki
@mohamad_elamki
Neurology department University Hospital of Zurich🇨🇭Group leader- ZNZ Zurich/ Cerebrovascular/ Blood flow/ Stroke 🧠 Science moved to Twitter, I moved too!
From our new paper @Cellreports, neutrophils get stuck in brain capillaries after stroke. @UZH_en @Unispital_USZ @UZH_IPT @SfNtweets @HerzstiftungCH #neuroscience #no_reflow
ECgo: All-Optical Induction of Single Endothelial Cell Injury and Capillary Occlusion in the Brain biorxiv.org/content/10.110… #biorxiv_neursci
You knock out #GLUT1 to impair astrocytic glucose uptake - only to find out that #astrocytes ramp up glycolysis and keep going. Metabolically resilient, and even neuroprotective. Our study in @NatureComms: nature.com/articles/s4146…
Astrocytic GLUT1 deletion in adult mice enhances glucose metabolism and resilience to stroke nature.com/articles/s4146…
Excited to share our new study showing that perivascular macrophages promote vascular function in the brain. A greater collaboration with the great Melanie Greter. Huge congratulations to everyone involved! @UZH_en @ImmunityCP
Online now: Interleukin-34-dependent perivascular macrophages promote vascular function in the brain dlvr.it/TKVG0s
Interleukin-34-dependent perivascular macrophages promote vascular function in the brain: cell.com/immunity/fullt… @ImmunityCP
🧠 Our new study in @JCephalalgia (journals.sagepub.com/doi/full/10.11…) explores genetic variants in FHM1-3 genes using @uk_biobank data. A genotype-first approach revealed that these 🧬variants ⬆️#migraine risk—and surprisingly, a link to ⬇️ #epilepsy was discovered. Here’s what we found🧵
So great to see our cover on the new @ImmunityCP issue! Kudos to the artistic touch of @Ales_matera ☺️ with @AnneCompagnion and the many collaborators! read more about microglia and Inpp5d (SHIP1) in brain development
New issue online! Cover depicts work from @rosa_paolicelli @Ales_matera @AnneCompagnion &co showing that Inpp5d (SHIP1) is expressed in microglia during early postnatal brain development, where it limits synaptic pruning in a complement-dependent manner. Cover shows microglial…
📆ny resolution REGISTER NOW in #phagocytes25 phagocytes2025.com 20 🔝speakers 28 short talks + posters 🌍Madrid @CNIC_CARDIO 📆26-28 March '25 Organized by @SEinmunologia Support by @CRC_TRR332 @TRR359_PILOT @inmunotek @EMBOevents Bursaries by @EFIS_Immunology @EurJImmunol
That was one of the best meetings I ever had! Thank you @AnnaDevor @davidkleinfeld @NelsonLab1 and all colleagues for the great discussions. I was honored by your invitation.
Thank you, Team USArhythms, Mark Nelson, Mohamad El Amki, @costantinoiade1 and all Blood Fest 2024 participants! Totally awesome talks and posters by trainees! I have a feeling that we are standing at the threshold of great things to come! :)
Please, RT If you love #macrophages #neutrophils #dendriticcells don't miss #phagocyte2025 📆26-28 March 2025 📍@CNIC_CARDIO Madrid 🌍top speakers phagocytes2025.com/index.php/spea… 🔬Submit your latest research for oral presentation or poster phagocytes2025.com/index.php/abst…
Happy to share our new paper published in @PNASNews. growkudos.com/publications/1… via @growkudos I am incredibly grateful to all co-authors and contributors @BrunoWeberLab @RazanskyLab @SuseWegener @UZH_IPT @Unispital_USZ
In our new study, we used fluorescent Localization microscopy to generate Hemodynamic maps of the whole Pial & Calvarial vascular connectome. Here, we used Pia-Flow in stroke, other applications for this transcranial powerful microscopy? #Topology #Velocity #direction #diameter
Can stem cells repair the stroke-injured brain? And what are the underlying mechanisms? We talk about evidence for direct cell replacement, release of supportive factors, safety, immune evasion, graft-host interactions and more! Published in @Brain1878 academic.oup.com/brain/advance-…
New lab preprint for those interested in #Angiogenesis and #notch signalling in the mature (healthy) mouse cortex. Congrats to the team, especially Ale and Ben for leading the work. biorxiv.org/content/10.110…
Did you know that if you ablate astrocytes, perlesional astrocytes divide and give birth to daughter astrocytes? A very exciting discovery from great colleagues. Kudos to @MatthiasWyss4 @BrunoWeberLab et al., #astrocytes #progenitors @UZH_IPT @UZH_ch
We’re thrilled to announce our latest preprint is now available on bioRxiv. Dive into our astrocyte research here: biorxiv.org/content/10.110…
New cover for Neuron! 🧠 Big Role of Tiny Blood Vessels🩸 Tiny vessels connecting arteries together can rescue brain after stroke! @mohamad_elamki and @susewegener found out that in stroke patients and mice, these tiny vessels (collaterals) regulate reperfusion after stroke.…
We present a major leap forward in large-scale transcranial fluorescence imaging of brain dynamics ! Kudos to Zhenyue Chen, Quanyu Zhou, Chaim Glück and the whole team 🎊 Another terrific collaboration with @mohamad_elamki, @SuseWegener nature.com/articles/s4146…