Jacob Kimmel
@jacobkimmel
Co-founder & President @NewLimit | Prev: PI @Calico, PhD @UCSF | Interested in aging, machine learning, genomics, the technology production function
ML in biology has been portrayed as a departure from tradition, but molecular biology emerged from a similar class of formal approaches. Framed differently, ML is helping us regain the formalism we lost during molecular biology's Golden Era: jck.bio/learning-repre…
NewLimit paper just dropped @icmlconf showing our SOTA AI models can predict perturbed cell states. Helps to have the largest primary cell perturbation dataset in the world. Bonus points for one of the first demonstration of active learning in bio.
~zero-shot Ab design is the next grand challenge in structural biology. these results are a leap forward & unlock previously intractable applications. congratulations to @chaidiscovery on the achievement. sentiment & technical reality have never been farther apart in biotech.
We’re excited to introduce Chai-2, a major breakthrough in molecular design. Chai-2 enables zero-shot antibody discovery in a 24-well plate, exceeding previous SOTA by >100x. Thread👇
it's always a good day when we expand the @newlimit fleet