Mark Painter
@markmpainter
Postdoc immunologist with @EJohnWherry at Penn, studying immune responses to SARS-CoV-2, viral infections, Long COVID, and beyond
I'm excited to see our work on immune responses during SARS-CoV-2 breakthrough infection out in @NatImmunol! The results highlight the broad benefits of vaccination and especially the role of memory T cells in the critical early stages of the infection. nature.com/articles/s4159…
Delighted to share our work developing an mRNA vaccine for C. difficile, published today in @ScienceMagazine. This study with @WeissmanLab was co-led by two truly amazing scientists: @_alexafluor from the Zackular lab and @MgAlameh (now at @CHOP_Research)! science.org/doi/10.1126/sc…
Very happy to share our new review on stem-like cells and their role in CD4 T cell differentiation in @TrendsCellBio cell.com/trends/cell-bi… It was great to tackle this topic with my prior mentor @HaydnKissick. Excited to share our thoughts!
1/n I don’t understand Dept HHS new position that childhood vaccines weren’t tested in placebo-controlled trials? That’s simply not true: here are some quick (non-exhaustive) PubMed searches beginning with the MMR vaccine
If you read one paper this week, make it this one!! Gorgeous mechanistic work—detailing how TOX not only initiates but maintains the cell fate of exhausted CD8 T cells—by an extremely talented scientist and good friend @jane__huang
Excited to share my graduate work from the @EJohnWherry lab on the molecular mechanisms locking in the differentiation fate of exhausted CD8 T cells (Tex), published earlier this month in @SciImmuno. Main findings below! science.org/doi/10.1126/sc…
Check out this excellent work on the role of TOX in already-exhausted T cells from @jane__huang!
Excited to share my graduate work from the @EJohnWherry lab on the molecular mechanisms locking in the differentiation fate of exhausted CD8 T cells (Tex), published earlier this month in @SciImmuno. Main findings below! science.org/doi/10.1126/sc…
Excited to share my graduate work from the @EJohnWherry lab on the molecular mechanisms locking in the differentiation fate of exhausted CD8 T cells (Tex), published earlier this month in @SciImmuno. Main findings below! science.org/doi/10.1126/sc…
"no one has died" because of feeding USAID to the woodchipper, Elon claimed. In this devastating piece the NYT went out and learned some of their names and stories:
Anyone left on Science Twitter who has spike specific CD8+ T cells? Wonder how you made them? Wonder no more. #27 @CytokineSociety @jkagan1 @Lo_Zanzi biorxiv.org/content/10.110…
Honored to be included in this work published in @CellCellPress. Congrats Hua! cell.com/cell/fulltext/…
I am so excited to share my first author publication, “Differentiation fate of a stem-like CD4 T cell control immunity to cancer” published today in @nature, detailing the project I’ve been working on in @HaydnKissick’s lab. tinyurl.com/33d24k89
Check out our latest paper “Differentiation fate of a stem-like CD4 T cell control immunity to cancer”, led by @Maria_Carden1 now live @Nature tinyurl.com/33d24k89 . This work examines how CD4 T cell differentiation dictates the outcome of the cancer response. Thread below
The Institute for Immunology and Immune Health (I3H) is proud to unveil our new website. Discover our innovative research and stay updated on the latest in immunology and immune health. Visit us at med.upenn.edu/i3h/
Very cool single-cell visualization package with support for TCR/BCR analysis and compatible with scRepertoire. Blown away by some of the viz ideas repo: github.com/pwwang/scplott… site: pwwang.github.io/scplotter/inde…
The @iedb is a world -renowned database of experimentally-validated, manually-curated immune data including #Tcell and #Bcell epitopes. It also hosts an analysis resource-tools used for immune-related predictions. Register now if you want to make the best use of this resource!
The IEDB Virtual User Workshop starts in 3 weeks! Register now so you don't miss out on hearing from our wonderful PIs @SetteLab and @BjoernPeters2, team members @jgbaum @ZeynepK_Y @mahitajarjapu @Alba_Grifoni @EveRichardson20 @danielmarrama & many more! surveymonkey.com/r/IEDBUW2024
Excited to announce the PolyBio Fall Symposium. It will take place Friday November 8th from 11 am - 5 pm ET. Join to hear PolyBio-supported investigators give short updates on their projects. Register here: us02web.zoom.us/webinar/regist…
Come work with me in The JCC Lab at @stjuderesearch. I’m #nowhiring a sr. scientist focused on applied integrative biology, a sr. bioinformatics research scientist in integrative analysis, and a sr. scientist focused on next-gen immunology. tinyurl.com/jxezsb3k #ECI2024
1 million paired TCR sequences for < $200. Congrats @PGTimmune and team biorxiv.org/content/10.110…
#LongCOVID causes perturbations that persist from 12 wks to >2 years, but does this impact #Tcells? Our study @PNAS from @KedzeriskaLab @DohertyInst defines long COVID T&B cell responses over 24 mths from epitope specificity to TCR clonotype doi.org/10.1073/pnas.2…
So excited to see our new study on #Tcells in #LongCovid published today in @PNASNews. Big thank you to @oanheei, @svalko3 and @KatherineKedz for championing the work.
#LongCOVID causes perturbations that persist from 12 wks to >2 years, but does this impact #Tcells? Our study @PNAS from @KedzeriskaLab @DohertyInst defines long COVID T&B cell responses over 24 mths from epitope specificity to TCR clonotype doi.org/10.1073/pnas.2…