Timothy Johnston
@timsjohnston
Graduate student @Penn, NIH Immunology, Virology, Vaccines
Wow. 7% is a big number. There are 100,000 dairy workers in the United States. 7% of 100,000 is 7,000 cases....a tad higher than the 46 H5 human cases reported in the United States. This is too many shots on goal, and I worry about a random mutation that increases human spread.
.@CDCMMWR : Serologic Evidence of Recent Infection with Highly Pathogenic Avian Influenza A(H5) Virus Among Dairy Workers - MI and CO Among 115 persons, eight (7%; 95% CI = 3.6%–13.1%) had serologic evidence of recent infection with A(H5) virus cdc.gov/mmwr/volumes/7… #h5n1
Honored to be included in this work published in @CellCellPress. Congrats Hua! cell.com/cell/fulltext/…
Fantastic review from @sarahcobey @NatImmunol covering vaccination and B cell memory to evolving pathogens like influenza and SARS-CoV-2! nature.com/articles/s4159…
Online now: Immunological imprinting shapes the specificity of human antibody responses against SARS-CoV-2 variants dlvr.it/T4C9rp
Here's a great article summarizing the findings! pennmedicine.org/news/news-rele… via @PennMedicine
Two new studies @ImmunityCP delve into the issue of #SARSCoV2 immune imprinting after infections and vaccinations ciell.com/immunity/fullt… @SCOTTeHENSLEY @timsjohnston @EJohnWherry @markmpainter cell.com/immunity/abstr… @veeslerlab
Excited to see this in @ImmunityCP! With @timsjohnston, Grace Li, @SCOTTeHENSLEY, and @EJohnWherry, we show how immune imprinting by mRNA vaccines enhances neutralizing responses to SARS-CoV-2 variants and how variant-specific responses can still emerge. cell.com/immunity/fullt…
Very excited to share our work released in @ImmunityCP ! Extending a special thank you to coauthors @markmpainter, Grace Li, and @IGGPenn mentors @SCOTTeHENSLEY and @EJohnWherry!
Check out our new @ImmunityCP manuscript, where we show that ‘immune imprinting’ with ancestral SARS-CoV-2 mRNA vaccines is beneficial for priming neutralizing antibody responses against emerging SARS-CoV-2 variants. 1/2 cell.com/immunity/fullt…
Sadly at the end of 2023, we passed the 7 million mark for the number of #COVID19 deaths reported to @WHO. 7,010,586 to be exact. The true death toll is higher, with estimates of at >3 times more deaths globally. 7 million… devastating. data.who.int/dashboards/cov…
There's no place like @PennMedicine for doing team science, and this was a great collaborative effort with @timsjohnston, Grace Li, @SCOTTeHENSLEY and @EJohnWherry.
Check out our new manuscript on @medrxivpreprint. We show that ‘immune imprinting’ with ancestral SARS-CoV-2 mRNA vaccines is beneficial for priming neutralizing antibody responses against emerging SARS-CoV-2 variants. 1/n medrxiv.org/content/10.110…