Luis E. Valentín-Alvarado
@luisarchaeota
microbial genomics, enzyme function research fellow @hfsp at @MonashBDI | microbial genomics PhD from @Banfieldlab @savagecatsonly at @UCBerkeley #firstgen
Humbled to be awarded the 2025 HFSP Long-Term Fellowship! Truly grateful for the opportunity to pursue bold science across borders. Excited to work with @gavinjknott on "Systematic discovery of evolutionary origins and functional diversity of methyltransferases" @MonashBDI
🥳Congrats to the 50 outstanding postdocs from 25 nations awarded 2025 #HFSPFellowships! 🎉These brilliant minds are shaping the future of #LifeSciences!🧪 🏆Are you one of them? Tag yourself & celebrate! 📖 Meet the fellows: hfsp.org/bookletFS2025#… #HFSP #NextGenResearchers
Our @MolecularCell Spotlight on the Hailong anti-phage system from the Kranzusch lab! This defense uses "ssDNA tripwires" to trigger toxic ion channels 🧬⚡☠️ Fun write with Johannes Kühn!!
(Hai)long story short: Phages trip the DNA wire—Snap! dlvr.it/TLn69h
An Asgard archaeon from a modern analog of ancient microbial mats biorxiv.org/content/10.110…
🦠What is microbiome research and what makes a good microbiome study? In their Editorial, the Senior Editors of Microbiome highlight the challenges of microbiome research and what they are looking for in submissions. 🚨Find out more: doi.org/g9fjn3
A comment I wrote for you is now online at @NatureComms: nature.com/articles/s4146… Oh, oh, it says "time travel will likely remain forever off the table in our universe" with a citation (poor scientist's click-bait 🥲).
RFdiffusion: Beta Documentation Now Available We’re excited to announce that RFdiffusion now has official, Rosetta Commons-curated documentation! Read more: rosettacommons.org/2025/07/16/rfd…
Comprehensive taxonomic identification of microbial species in metagenomic data using SingleM and Sandpiper nature.com/articles/s4158…
Fast, cost-effective and flexible DNA sequencing by roll-to-roll fluidics | Nature Methods nature.com/articles/s4159…
Nuclease-NTPase systems use shared molecular features to control bacterial anti-phage defense | bioRxiv biorxiv.org/content/10.110…
Ten simple rules for faculty members building just and equitable environments in academic science journals.plos.org/ploscompbiol/a…
Come join the bridge editing team @arcinstitute and build the future of genome design!
Happy to share that I'm continuing my research on bridge recombinases as a scientist in @pdhsu lab at the @arcinstitute! I am looking for a motivated post-grad to work with me as a research associate. If you are interested or know of someone, please use the link below:
Bay Area friends! I’ll be around for the next few weeks. If you’re nearby and want to catch up - science chats, hikes, coffee, or just vibes — send me a message. Would love to reconnect
Histone diversity in the archaeal domain of life | bioRxiv biorxiv.org/content/10.110…
Nice reference sheet to AI models for proteins: tamarind.bio/blog/a-compreh…
🌍 @Basecamp_Res has announced a series of new global biodiscovery partnerships—Malawi, Hungary, @Scripps_Ocean and @veritree —to accelerate the growth of it 9.8B protein sequence database and AI for drug discovery. Co-founders @glen_gowers & Oliver Vince news, shared the news…
Latest BREX story from the lab - turns out there is a nuclease after all! Congrats to Jenny Readshaw and the whole team, including wonderful collabs Barry Stoddard, Brett Kaiser and @DarrenSmithdx. @NAR_Open @NEBiolabs @DurBiol academic.oup.com/nar/article/53…
Deeply touched and honored by the Universidad Autónoma de Madrid, my alma mater, (@UAM_Madrid) making me Doctor Honoris Causa. Thank you to the Department of Physical Chemistry for nominating me for this recognition. It was a memorable day for me and my family👩🎓
Phage tRNAs: decoding the enigma dlvr.it/TLR23K
🎉New preprint!🎉 Extremely excited to share CryoBoltz❄️⚡️, led by superstar @rishwanth_raghu! We develop a multiscale guidance recipe to steer structure prediction models (e.g. AlphaFold3 / Boltz-1) towards experimental cryo-EM density maps, including heterogeneous,…
Excited to present CryoBoltz ❄️⚡, a multiscale guidance approach for steering AlphaFold3/Boltz-1 to sample structures that are consistent with experimental cryo-EM density maps. 🧵1/7 arxiv.org/abs/2506.04490 Joint work with @axlevy0 @GordonWetzstein & @ZhongingAlong!
Phylogenomic analyses indicate the archaeal superphylum DPANN originated from free-living euryarchaeal-like ancestors nature.com/articles/s4156…
Abundant and metabolically flexible bacterial lineages underlie a vast potential for rubisco-mediated carbon fixation in the dark ocean | Genome Biology | Full Text genomebiology.biomedcentral.com/articles/10.11…