Rosetta Commons

We are very excited to announce that early bird registration for European RosettaCon 2025 is now open! More information here: europeanrosettacon.org

Registration for Biomolecular Modeling and Design with Rosetta and ML Tools Workshop (November 17th – 19th, 2025) is now open. The goal of the workshop is to educate and train academic and industry users on the Rosetta software suite. Explore more: meilerlab.org/tutorials/

We're excited to introduce our #RaMP 2025-2026 cohort. Watch this space for more updates.

RFdiffusion: Beta Documentation Now Available We’re excited to announce that RFdiffusion now has official, Rosetta Commons-curated documentation! Read more: rosettacommons.org/2025/07/16/rfd…

We listened to your feedback. Proscuplt is: *Easier to install - now uses use containers 🚀 *Easier to run in SLURM - specify queue & task details directly in the prosculpt YAML file. github.com/ajasja/proscul… Big thanks to @FAOlivieri_, @Alina_K_KI, Nej Bizjak, and Žan Žnidar🙏

We’re making a few intentional changes to our US-based Rosetta conferences next year to better support our growing community. We want to hear what you think. Learn more about the changes: rosettacommons.org/2025/06/26/loo… Share your thoughts: docs.google.com/forms/d/e/1FAI…

Rosetta Commons Biosecurity Fellowship now accepting proposals This 12-month remote fellowship offers a unique chance to shape how protein design tools are developed and governed. Fellows lead their initiative, engage directly with Rosetta Labs and policy experts, and help…

50% and higher experimental success rates would be a game changer and absolutely amazing. I just hope it's not a training set leak or some other artifact (since binders to all of these have been designed before). Hope the scientific community can get access soon to test.

News from the Rosetta community: Prosculpt – an open-source library integrating RFDiffusion, ProteinMPNN, AlphaFold2 & Rosetta into one easy workflow More via @AjasjaLjubetic: rosettacommons.org/2025/05/28/all…

Early bird registration for 𝐄𝐔 𝐑𝐨𝐬𝐞𝐭𝐭𝐚 𝐂𝐨𝐧 𝟐𝟎𝟐𝟓 is open! 🎉🎉🎉 Come join us for three days of protein design fun! (October 20-22, 2025) Direct registration link: pretix.eu/SBD/RCon2025/ Website: europeanrosettacon.org We are looking forward to seeing you!

Our Rosetta Commons Research Experience for Undergraduates (REU) students have completed the first leg of the program with the @jeffreyjgray lab at The @JohnsHopkins University and are now heading to their host labs for the summer. Stay tuned for more!

How to train your model. This immersive, hands-on, advanced-level event is designed for researchers who are ready to move beyond “out-of-the-box” machine learning models for protein design. Join us for this Summer RosettaCon 2025 workshop/hackathon, more here:…

Consider joining us for the 2025 Summer RosettaCon's 1-day Protein Design AI-Driven Design of Biologics: Hands-on Guide to Using State-of-the-Art ML Protein Models brought to you by the Rosetta Commons. One-day novice-level course surveying popular tools and workflows for modern…

Fun podcast about our @HomeworldBio & @ICGEB funded research on plastic-degrading enzymes at @iibm_uc @ucatolica, our open science work on molecular diagnostics with @reclone_org @LabTecLibre and our education efforts on AI protein design in Latin America w/@EMBO @RosettaCommons!

One-day novice-level course surveying popular tools and workflow for modern protein design with brief exploration of common applications including antibody design and binder design: 1-day Protein Design Workshop. Register here: tinyurl.com/SRC25-workshop1

Register for SRC25 Workshop (tinyurl.com/SRC25-workshop2) : How to train your model - This immersive, hands-on advanced-level event is designed for researchers who are ready to move beyond “out-of-the-box” machine learning models for protein design. Participants will gain practical…

Come hang out with us — Registration for Summer RosettaCon 2025 is open! It will be held at Suncadia Resort in Washington from August 4 - 7, 2025. Register here: rosettacon.org