Kamen Simeonov

Check out our new review/opinion on molecular recording of transcriptional events by @sierra_lear. We write about where the field is, where it might be going, and what's stopping us from being there now. sciencedirect.com/science/articl…

Kawhi just snuck in #TrustTheProcess in the postgame presser. Dropping hints? @SpikeEskin @JashFath

Thrilled to share a preprint (biorxiv.org/content/10.110…) combining single-cell RNA-seq and multiplex reporter assays. Amazing collab with stem cells and genomics wizard @SRegalad0, and many folks in @JShendure lab. (1/14)

Today we release in @biorxivpreprint a pair of related methods, DNA Ticker Tape & ENGRAM, for multiplex, temporally ordered genomic recording of cell lineage histories, enhancer & signal transduction activities, respectively led by the brilliant @_Choi_Junhong & @wchenomics 1/25

Very excited to share my PhD work on how glia promote traumatic brain injury (TBI) recovery but chronically accelerate degenerative tau pathology: rdcu.be/cnZRB. Out tomorrow in @NatureAging

We used our Azimuth human lung reference to map 1M cells (10 studies, >200 donors, 8 disease states) into a common space with harmonized annotations and visualization. You can explore the results using the @cziscience cellxgene platform at cellxgene.cziscience.com/e/f72958f5-7f4…

You can install Seurat v4 and check out new vignettes for multimodal analysis at: satijalab.org/seurat You can explore our CITE-seq dataset and the expression of your favorite gene (or protein!) at this beautiful web portal designed by Michael Zager: atlas.fredhutch.org/nygc/multimoda…

Single-cell lineage and transcriptome reconstruction of metastatic cancer reveals selection of aggressive hybrid EMT states biorxiv.org/cgi/content/sh… #bioRxiv

Excited to share our work exploring cancer metastasis & EMT at single-cell resolution via CRISPR lineage tracing in the Lengner lab @Penn in collab with @JShendure @aaron_mckenna, @chinabyrns, @megclarks, Bobby Norgard, @bethkarenmartin & Ben Stanger biorxiv.org/content/10.110…

A marine biologist films this octopus changing colors while dreaming and it’s spectacular

In this work, we profile over 500,000 cells with special emphasis on the adult mouse brain and human bone marrow in native and stimulated settings. Read more here: biorxiv.org/content/10.110… 2/4

.@PennDPS @Penn @BikePHL: was biking a few minutes ago behind Smilow where I work on Health Sciences Dr. Driver beeped & screamed at me for biking on the road. No bike lane & hundred of Penn folks bike this road everyday. Crossing guard said it was a Penn Park & Ride bus.

Just saw this trumpybear ad on tv: youtube.com/watch?time_con…

So are we going to talk about this as much as yesterday's play? Lost all respect for the salty #Spurs and Pop streamable.com/lcr29

Kitini's interest was piqued by the #planetearth2 snow leopard mating scene