Katherine A Donovan
@kdonovan1008
🇳🇿 Kiwi | Scientist @DanaFarber @harvardmed | Targeted Protein Degradation | Chemoproteomics | Tweets are my own | find me on🦋
Excited to be hosting next week’s DFCI TPD seminar! We’ll hear from two outstanding speakers, Rebecca Metivier and Martin Steger who will share their work on developing and applying mass spectrometry-based proteomics platforms to identify and catalog degrader targets.

🧩 New paper out in Nature Communications! "Unveiling the hidden interactome of CRBN molecular glues" Huge thanks to our incredible team and collaborators who made this possible! 📖 Read the full open-access article here: nature.com/articles/s4146…
Our proteomics group is looking for a Scientist who is excited to push the boundaries of chemoproteomics and interactomics at Dana‑Farber! Apply at the link or message me with questions! careers.dana-farber.org/job/11894/scie…
🚀 Join us for the last DFCI Targeted Protein Degradation (TPD) Seminar before our summer hiatus! 🗓 Date: July 24th We are very excited to be hosting two fantastic speakers Jonathan Bushman (@Amgen) and Guillaume Lessene (@WEHI_research)

🎉 2025 DFCI TPD event registration is open! 📆 Sep 11, 11:30 AM–8 PM ET, Boston 🔑 Keynote: Nathanael Gray 📝 Registration link: forms.gle/NLUSa51Btrtf6F… #TPD #ProteinDegradation #DrugDiscovery #Boston #DFCI

Join us for the next DFCI #TPD Seminar — July 10, 2025! Chemoproteomic-Enabled Development of Proximity-Inducing Molecules Christopher G. Parker, Scripps Research Details: …afarbertargetedproteindegradation.org Don't miss it!
Join us for the DFCI #TPD seminar this Thursday! We’ll hear from two outstanding speakers: 1) Kimberly Stegmaier @KStegmaier_DFCI will discuss targeting fusion TFs 2) Leo Kiss @MPI_Biochem will share insights into the ubiquitin code Tune in 👉 bit.ly/3OmMRjp
Excited to host a TRIM21 double webinar! 🔬 Ting Han (NIBS): Glues & PROTACs for multimeric proteins 🔬 Drew Adams (CWRU): TRIM21 degraders 📅 June 12, 12PM EST 🆓 Open & free Register: …afarbertargetedproteindegradation.org
Tune in this Thursday for two great #TPD talks: 1) Maria Rodriguez-Rios & Conner Craigon @dundeeuni @UoDCeTPD will discuss BromoCatch 2) Mark Mabanglo & Mahmoud Noureldin @OICR_news will present DCAF1-PROTAC-WDR5 structures 👉Join us on May 29th at 12 PM EST/ 6 pm CET
📢 Save the Date! The next FREE Dana-Farber TPD In-Person Event is coming soon! Join us for an afternoon of cutting-edge science, networking, and community building focused on Targeted Protein Degradation (TPD). Stay tuned for registration and speaker details.

Join us on April 17th for an exciting double seminar from the University of Dundee @UoDCeTPD: @CharlCrowe on "Mechanisms of degrader-targeted protein ubiquitinability" and @ales_salerno on "FerroTACs." Details: …afarbertargetedproteindegradation.org
Happy to share that Dr. Peng Chen and Chase Suiter will be joining us to speak about their work in the TPD space on April 3rd at 12PM EST!

I am very excited to be hosting Prof. Jian Jin in our TPD webinar series on March 6th at 12pm! Join us to hear about his lab's strategies to target undruggable proteins

Very excited for our next seminar next week! Yuh Min Chook(@yuhminchook) at UTSW will share an intriguing allosteric mechanism of drug-induced XPO1 degradation, mediated by the CRL5-ASB8 E3 ligase complex. Join us at 12 pm EST (Feb 20th). Preprint - biorxiv.org/content/10.110…
My lab at @MDAndersonNews is actively seeking motivated individuals (Postdocs, RAs, Scientists) interested in TPD, induced proximity, or small molecule drug discovery. (1/6)
Attention APS members. Award applications for Students, ECRs and MCRs are now open! #AUSoMicS
Honored to be giving a talk at Dana-Farber’s TPD seminar this Thursday 2/6 at 9am PST. dfci.zoom.us/webinar/regist… Come check out MrTAC 💊@DFCI_ChemBio
Awesome job opportunities in the Xiao lab at Stanford!
Excited to share that the Xiao lab is launching at @StanfordBiochem and @StanfordCancer this fall! We will be soon seeking a research technician and a postdoctoral fellow. If you are interested, feel free to email me and I'd be happy to chat! More info: xiaolab.space
New #PROTAC preprint: In this work, we utilized a non-selective ethyl hydrazide warhead for the selective HDAC6 degradation. Congratulations to co-first authors Daniel @danicious & Irina as well as Felix @fellerflix ! go.shr.lc/4jinjC0
Thrilled that I have been awarded the NIGMS K99/R00 Pathway to Independence Award to study transcription on a molecular level. Grateful to my mentors @fischerlab1 | @Armstrong_dfci and all my colleagues for their incredible support! @NIGMS @DFCI_CancerBio @DFCI_ChemBio