Zuzanna Kozicka

More cyclin K degraders! Loved contributing to this study showing how binder derivatisation unlocks gain-of-function activities in the right systems. Beautiful chemistry led by @zhezhuang7 - I am a big fan of the acrylamide π-system examples: double bonds ≠ just warheads💡

Join us for the DFCI #TPD seminar this Thursday! We’ll hear from two outstanding speakers: 1) Kimberly Stegmaier @KStegmaier_DFCI will discuss targeting fusion TFs 2) Leo Kiss @MPI_Biochem will share insights into the ubiquitin code Tune in 👉 bit.ly/3OmMRjp

Tune in this Thursday for two great #TPD talks: 1) Maria Rodriguez-Rios & Conner Craigon @dundeeuni @UoDCeTPD will discuss BromoCatch 2) Mark Mabanglo & Mahmoud Noureldin @OICR_news will present DCAF1-PROTAC-WDR5 structures 👉Join us on May 29th at 12 PM EST/ 6 pm CET

📢 Save the Date! The next FREE Dana-Farber TPD In-Person Event is coming soon! Join us for an afternoon of cutting-edge science, networking, and community building focused on Targeted Protein Degradation (TPD). Stay tuned for registration and speaker details.

Very excited for our next seminar this Thursday (March 20th): Martin Schwalm (@thesgconline, form. Knapp lab) will discuss UPS inhibitors and @DeanClift1 (@TRIMTECHtx) will share insights on hijacking TRIM21! 👉Join us at 12 PM EST/ 5 pm CET (‼️US/EU daylight saving mismatch‼️)

Join us for the final TPD webinar of 2024 on 12/19. @FleurMFerguson & @eswang01 - "ZBTB11 Degraders Target Metabolic Vulnerabilities in K-Ras Inhibitor Resistant PDAC" Slava Ziegler - "Targeting IDO1 by monovalent degraders exploiting the native IDO1 degradation mechanism"

📣 Please share: We’re hiring a tenure-track Group Leader in Multicellular Systems to explore the molecular and cellular mechanisms driving the formation, maintenance, or destabilization of tissues, organs and organisms. Apply at: fmi.ch/education-care…

It seems that the big migration is finally happening 🦋 And it feels just like #scienceTwitter did a few years ago! If (when...?) you join make sure to follow the #TPD starter pack: go.bsky.app/FreGFDW

We are thrilled to have @georg_e_winter @CeMM_News return to the DFCI TPD webinar this Thursday! Georg will talk about how inhibitors can supercharge endogenous degradation mechanisms. Very much looking forward! 👉Join us at 12 PM EST/ 6 pm CET (hybrid format)

Very excited for our next seminar this Thursday: Derek Bartlett (formerly @pfizer, now @UNC) will share insights on PK-PD modelling for TPD and Kyle Mangano (@Amgen) will present how VIPER-TACs co-opt viral E3s. 👉Join us at 12 PM EST/ 6 pm CET (back to original schedule)!

We are very excited to announce our next in-person #TPD event - join us for half a day of science and networking in Boston on September 12th! 🥳 Register here (free thanks to our sponsors): forms.gle/a8p2ALX9n2YDWt…

Exciting double #polymerisation seminars this week! Join us on Thursday, July 25th at 11 am EDT to hear the duo of @jihojasonpark and Paul Park from @DanaFarber as well as @MSuskiewicz from @CNRS talk about homomerising transcription factors. 👉 bit.ly/3OmMRjp

Recently finished your PhD? Why not spend the next few weeks writing it up into a short, accessible essay? Who knows, it could be published in @ScienceMagazine and get you invited to participate in the @NobelPrize festivities! Due July 15th - give it a try! 😊 @SciLifeLabPrize

Tune in to the @danafarber #TPD webinar this Thursday to listen to two great talks: Elisia Villemure from @genentech presenting a molecular glue degrader working via FBXO22 and Kyle Seamon from Revolution Medicines talking about gluing #KRas 👉Join us bit.ly/3OmMRjp

An inspiring discussion today at the @DanaFarber’s Helen Gurley Brown Presidential Summit with four fantastic scientists and leaders @LGlimcherMD, Alexa Kimball, @jean4neuro, and @FionaHMarshall. Great community and valuable lessons in how we can pull each other up! #womeninSTEM

The final song of the Gala Dinner ceilidh! Auld Lang Syne - traditionally played at Hogmanay (New Year's Eve) - also captures the spirit of the meeting. Induced proximity at its' very finest! 🙏🤣 Thanks for sharing @NikolasKlink ! #TPDFocus