joe
@jtyler91
Big dumb scientist. Biochemist/cell biologist
In my opinion, one purpose of poetry is to express something that can’t be described within our ‘normal’ manners of expression. This is something that Isn’t necessarily ’enjoyable’. Understanding is forged in contradiction… Reproduction of style is meaningless
The real underlying problem is that humans just absolutely love slop
Imagine this was a 4-year-old you know. Actually imagine it haaretz.com/opinion/2024-1…
Joe Tyler @jtyler91, Anthony Davidson, Vassilis Koronakis & team find that inhibition of PAK activity leads to the production of PI(3,4,5)P3 at the plasma membrane & a dysregulation of the actin cytoskeleton. journals.biologists.com/jcs/article/13… Article: journals.biologists.com/jcs/article/13… #OpenAccess
Evaluating different deconvolution algorithms today. Behold the power of Richardson-Lucy!
Actin waves + inverted LUTs 🤩 (bonus points if you can guess the cell type)
Now online! Genetically encoded reporters of actin filament organization in living cells and tissues dlvr.it/TJzW5F
NHSL3 interacts with Ena/VASP proteins and the Scar/WAVE complex and promotes cell migration. biorxiv.org/content/10.110… #biorxiv_cellbio
A long-awaited mechanistic analysis of small GTPase biology and membrane pattern formation by the labs of Peter Bieling and Bill Bement @BementLab embopress.org/doi/full/10.10…
🚨Long term postdoc position available on the reconstitution of lipid kinases!🚨 Do you have a passion for protein reconstitution and lipid signalling? You will reconstitute lipid kinases to determine their kinetic regulation. jobs.ac.uk/job/DLW981/res…
Excited to share my first contribution to virology, 1 year into my postdoc @towerslab! Together with my colleague @kate_morling, we review latest advancements of how HIV capsid and accessory proteins Vpx/Vpr have evolved to regulate host innate immunity. microbiologyresearch.org/content/journa…
Congratulation Mubarak (Kai Erdman's lab) on passing your PhD viva today!!!! 🎉 @ScienceShef @sheffielduni
Spatial organization of PI3K-PI(3,4,5)P3-AKT signaling by focal adhesions sciencedirect.com/science/articl…
Screen for novel kinase regulators by @Montse_Llanses @ERainero_lab &co shows that the α2β1 integrin/p38 signaling axis is needed for internalization of #integrin-bound #ECM, modulating cell migration & invasion in diverse #cancer cells #PLOSBiology plos.io/4gzKTbp
Great day at #actin2024 featuring lots of v cool talks, including our very own @rachellawson954, @ZheBao_Sheff and @jtyler91 ✨
Please enjoy this movie of local #microtubule disassembly inside the yellow circle using #optokatanin (magenta) with ER labelled in cyan & please give me a follow on Bluesky! joycemeiri.bsky.social
نور حب ماما وبابا غادرت متألمة، مثخنة بجراحها نحو السماء .. Noor, a young child from Gaza, was killed by an Israeli bombing. When they found her lifeless body, they saw the tender words she had written on her small hand: “Noor loves Mama and Baba”
Nearly 70% of Gaza war dead are women and children, UN says bbc.in/4fH3RfP
Check out the latest work from @WUMIN_LAB on the competition and synergy of Arp2/3 and formins in nucleating actin waves driven by @XiangLeJerry! 🎉🎉🎉
Competition and synergy of Arp2/3 and formins in nucleating actin waves dlvr.it/T9BbXW