Joy Pai

Are you or someone you know applying to @stanfordimmuno's PhD program this fall? Join SIRPA to get Statement of Purpose feedback and a 1-1 session with a current Stanford Immunology PhD student! First-come first-served until November 5th.

Out on @biorxivpreprint, I'm excited to share our latest deep dive into the world of mitochondrial genetics using single-cell genomics. Grateful to have worked with @LeifLudwig, @Satpathology, and many others. biorxiv.org/content/10.110… Thread here: 1/n

Out today in @NatureProtocols, our detailed writeup on the mitochondrial scATAC-seq assay, spanning everything from the molecular biology to computational analyses. Check out the paper here: rdcu.be/c5HAJ and some highlights in this thread: (1/11)

Happy to share that our work is online @MolecularCell. Our single-cell chromatin atlas of macrophage polarization reveals cyclical macrophage plasticity states in cell cycle. Great collaboration with Julia Belk, @HowardYChang & @Satpathology. cell.com/molecular-cell…

Excited to share the latest preprint with @MikeAngeloLab! While imaging studies often focus on cell objects, images capture significant info outside of cells. Enter Pixie, a pipeline for the quantitative annotation of both pixel and cell level features🧵biorxiv.org/content/10.110…

Our lab thinks a lot about the epigenetic regulation of T cell exhaustion. Happy to have a chance to discuss important prior work that has influenced our thinking as well as our own speculations in @NatImmunol. Led by Julia Belk and @BenceDaniel2 nature.com/articles/s4159…

Our work on CD4 T cell responses to persistent antigen is out now! Grateful to Yu Xia @SandorDanielne @BenceDaniel2 @Satpathology and @FW14B_Red5 for the great collaboration.

Check out this amazing work on the epigenetic programming of TRMs, led by my lab-mate and friend @buquicchioli!

Excited to share our preprint on clonal T cell differentiation trajectories of T cell exhaustion. Great collaboration with @KatieEYost @HowardYChang @FW14B_Red5 @Satpathology and others @StanfordMed. biorxiv.org/content/10.110…

New preprint!!! Here we show how transient activation of dendritic cells diversifies T cell fates. A thread in english y también en español! biorxiv.org/content/10.110…

Very excited to share our work on regional T cell clonal dynamics in lung cancer! Honored to be able to work with and learn from @AndrewChowMDPhD, Matthew Hellmann, @Satpathology, @charlesrudin, @merghout, @wolchokj, and many more.

Happy to share recent work from @SandorDanielne @joyp_ai @BenceDaniel2 in collaboration with the Egawa lab @FW14B_Red5 identifying a TCF1+ CD4 progenitor that maintains long term responses to chronic antigen

Excited to share our review of TCR sequencing technologies out now in @naturemethods! nature.com/articles/s4159…