Inigo Martincorena

Excited to share our latest work. We introduce an improved version of NanoSeq, a duplex sequencing protocol with <5 errors per billion bp in single DNA molecules, and use it to study the somatic mutation landscape of oral epithelium in >1000 people. 1/n medrxiv.org/content/10.110…

🦍Postdoc in Somatic Evolutionary Genomics🦍 Join my team @GeneticsCam on a pioneering project mapping somatic mutations across primates! 🌍Collaborate with experts @UCBerkeley & @sangerinstitute. 🔍Experience in genomics? Apply by Nov 16! Details: jobs.cam.ac.uk/job/48757/

I have joined Bluesky and it has been wonderful to see so many friends and colleagues there that had stopped engaging with X / Twitter, and to feel again at home. If you follow me here, feel free to find me in Bluesky too. 🦋

I'm a PhD student at @UniofOxford and I think I'm living in a fairytale :-) Foxes playing around in the snow at Magdalen College this morning — absolutely magical!

PhD and Postdoc positions available! Interested in how our immune system evolves with a growing tumour, and how we can use that to fight cancer? Love data analysis? Applications now being accepted in the Machado Lab (machado-lab.org/contact) at the University of Cambridge.

Stem cell transplants are amazing. A patient's diseased blood is replaced by a relative or stranger's. But what does putting a blood system into a new body do to the cells? How many survive? Does it matter? Out in @Nature today, we asked some basic Qs 👇 rdcu.be/dYCoZ

II'm excited to finally share our study on the mutational landscape and selection dynamics in sperm, now live on medRxiv: medrxiv.org/content/10.110…. We explored how positive selection impacts mutation rates, especially with age. Here’s a quick thread on our findings! 🧵👇

Very happy and excited to announce that I'll be starting my own research group at @emblebi! The group will focus on lineage tracing, somatic evolution and the origins of cancer. Interested in doing a postdoc in the group or know someone who is? Please reach out!

Excited to share our new preprint in which we address: (1) Accurate sequencing of sperm at scale (2) Positive selection of spermatogenesis driver mutations across the exome (3) Offspring disease risks from male reproductive aging [1/15] medrxiv.org/content/10.110…