Tim Coorens

Very happy and excited to announce that I'll be starting my own research group at @emblebi! The group will focus on lineage tracing, somatic evolution and the origins of cancer. Interested in doing a postdoc in the group or know someone who is? Please reach out!

Check out our new paper in @nature nature.com/articles/s4158…. We report genetic mechanisms of neural tube defects in patients. Spina bifida is also known as meningomyelocele (MM). Prior family-based and association studies found few linked genes, so we took a different approach.

🧬 The SMaHT marker paper is now live in @Nature This landmark study characterizes somatic variation across 19 tissue types from 150 nondiseased donors, laying the groundwork for future discoveries in health, aging, and disease. Read the full paper: nature.com/articles/s4158…

This Monday at CIMUS @TimCoorens from @emblebi

Thrilled to see #SAVANA out in @naturemethods🥳 SAVANA detects haplotype-resolved somatic SVs and copy number aberrations (SCNAs) and infers tumour purity & ploidy in clinical samples using long-read sequencing with or WITHOUT a matched germline control 👇nature.com/articles/s4159…

1/ 🧵Check out our new study in @NatureGenet, which examines how precancerous conditions (MGUS/SMM) evolve into Multiple Myeloma, and offers new computational methods to predict progression risk and model cancer evolution. doi.org/10.1038/s41588…

Call for Papers! @genomeresearch is now encouraging submissions for a Special Issue on The Genetics and Genomics of Somatic Mosaicism, Guest Edited by Drs. @giladevrony, @EAliceLee2, and @R_Rahbari. tinyurl.com/Call-for-paper… #BOG25 #KSMosaicism25 #MITS25 #somaticmosaicism

@AACR Seeing friends and gushing about our shared love for DNA 🤓🧬😃🤟@TimCoorens @imartincorena @ivazquezgarcia #AACR25

🚨OPEN POSTDOC POSITION in our brand new lab space by Madison Sq NYC ! 🌆🧬🔬 Do experiments, learn computation, and uncover drivers of a major mutational process affecting >50% of cancers, driving therapy resistance & impacting immunotherapy responses👇 med.nyu.edu/research/postd…

This new paper @Nature today on the genesis and evolution of stomach cancer goes against the alt-model nature.com/articles/s4158… nature.com/articles/d4158…

For the first time, scientists have analysed mutations in stomach lining tissue to reveal the earliest stages of cancer. The team also uncovered a potential new cause of stomach cancer, which needs further research 🔎 sanger.ac.uk/news_item/earl…

Happy to see our new paper out! A great collaboration with @jeshoag. We collected sequential sperm samples separated by decades, and used high-fidelity sequencing to measure germline mutation rates in individual men. nature.com/articles/s4146…