Alex Cagan

Incredibly excited to share our paper ‘Somatic mutation rates scale with lifespan across mammals’ now published @nature. nature.com/articles/s4158… An illustrated & updated tweetorial… [1/24]

Two days remaining to apply for a Postdoc in my team exploring somatic mutational landscapes across primate species. The position is based @GeneticsCam and will involve collaboration with @sangerinstitute and @UCBerkeley

🦍Postdoc in Somatic Evolutionary Genomics🦍 Join my team @GeneticsCam on a pioneering project mapping somatic mutations across primates! 🌍Collaborate with experts @UCBerkeley & @sangerinstitute. 🔍Experience in genomics? Apply by Nov 16! Details: jobs.cam.ac.uk/job/48757/

What Earth’s biggest animals could teach us about beating cancer 📰(£) Rhys Blakely @thetimes writes about Alex Cagan's (@ATJCagan) work exploring cancer resistance across the animal kingdom ⤵️ thetimes.com/uk/science/art…

I wrote up a presentation from a recent @CR_UK workshop on 'the biology of ageing to cancer prevention' into my first post on substack open.substack.com/pub/alexcagan/…

Spread the word! Registration for the "Mutations in Time and Space" conference is open. The meeting is all about the origins, patterns, and consequences of mutations across cells, individuals, populations, species. Abstract submission deadline: Jan 17th broadinstitute.swoogo.com/mits2025/597...

Join us! The Machado Lab at @Cambridge_Uni is looking for an enthusiastic RA to be a core member of the team and lead the lab's data generation efforts, seeking to understand how tumour and immune cells co-evolve and contribute to cancer progression. jobs.cam.ac.uk/job/47922/

Enjoyed working with @genomeresearch to design the cover for their special issue on Long-read DNA and RNA Sequencing genome.cshlp.org/content/34/11.…

Last chance to apply for our fully funded PhD (thanks @CamPhilSoc), welcome to *all students* on somatic evolution in plants. Come and work with me @ARU_Biology and Alex @ATJCagan @GeneticsCam Deadline tomorrow midnight! findaphd.com/phds/project/s…

Great illustrated summary of my talk at #ASHG24 from @PhDood1es

Talk by @TimCoorens on charting landscapes of somatic mutation with the SMaHT consortium #ASHG24

Laura Conlin on mosaicism in a diagnostic setting #ASHG24

Luis Paulin on detection of mosaics structural variation with Sniffles2 #ASHG24

Christopher Walsh on somatic monasticism and its link to disease in the human brain #ASHG24

Duncan Palmer on the biobank rare variant consortium powering the discovery of rare genetic associations #ASHG24

Giovanni Quinones-Valdez on long read RNA seq to study alternative splicing #ASHG24

Nahyun Kong on the genetic architecture of congenital heart disease in relation to uniparental disomy #ASHG24

Talk by Rajiv McCoy on the genetic architecture of meiotic recombination from over 100,000 in vitro fertilised embryos #ASHG24

First plenary session talk by Marie-Julie Fave on mosaic chromosomal abnormalities in blood across ancestries #ASHG24

Great to see this milestone study by @MDC_Neville and @R_Rahbari on postive selection in the male germline finally out. It sheds light on the origins of paternal age associated disorders. Great to have been involved in. See tweetorial here:

PhD and Postdoc positions available! Interested in how our immune system evolves with a growing tumour, and how we can use that to fight cancer? Love data analysis? Applications now being accepted in the Machado Lab (machado-lab.org/contact) at the University of Cambridge.