Gleb Kuznetsov
@glebkuz
Co-Founder and CEO @ManifoldBio
Proud to partner with @glebkuz and the brilliant team at @ManifoldBio on the launch of their new brand and website - manifold.bio A company designing smarter biologics—starting where it matters most: inside living systems.
Excited for this science event we're hosting today:
Manifold Bio is hosting a Science Hour today (7/16) at 6pm ET (3pm PT). Special guest Emerson Glassey will present his library-guided peptide engineering work. Our in-person event is full, but you can join virtually at the Zoom here: lu.ma/rh9atiiv
For a platform therapeutics company as technologically rich and fast-moving as Manifold Bio, a website is always just a snapshot in time. But I’m especially excited about this one. Our goal was to capture the scale of the tissue-targeted medicines opportunity and the uniquely…
We're live! Manifold Bio's new website is here: manifold.bio Inspired? We're growing—join us. Special thanks to @bunsenstudio for articulating our vision and Javelin Tea Creative (javelinteacreative.com) for capturing the spirit of our team. #Hiring
When you're trying to do something hard, you need the best people who are not afraid to find and develop even better people. A pleasure building a generational company alongside @alexcampreis.
May marked my 4 year anniversary with Manifold. As part of comp, employees at biotech startups often receive stock options. And if you’re familiar with options vesting, you may understand why continuing to stay after 4 yrs means something /1
The same archetype is emerging in drug discovery among teams that can rapidly generate data. The same person can generate designs, rapidly grok new data integrated with historical data, and iterate on models, molecule designs, and follow-up experiment designs.
There’s a new breed of GenAI Application Engineers who can build more-powerful applications faster than was possible before, thanks to generative AI. Individuals who can play this role are highly sought-after by businesses, but the job description is still coming into focus. Let…
To predict the future in biotech, study and understand the tools. Stories of new drugs, platforms, data generation strategies are usually stories of new measurement techniques. Progress in assay development has been breakneck this past year but masked by widespread industry…
Great lab and mentor to consider for Yale students interested in synbio / developmental biology.
a personal update: in January, I'm moving to Yale to join @MCDB_Yale and to open my lab in the @WuTsaiYale Institute! We will investigate multicellular self-organization using synbio tools to read and write developmental signals in stem cell models. syndevbio.org
Many new machine learning tools for protein engineering have popped up in the last year. In these early days, it might be unclear how to actually use them for real molecular design tasks in industry. We demonstrate how to engineer a cholesterol drug and plastic degrading…
Great to hang out with Gleb and Pierce @ManifoldBio on a beautiful day in Boston!
veni, *vivo*, vici
Most companies are leveraging DNA barcoding to do in vivo multiplexing, but Manifold is unique - protein barcoding allows quantitative tracking of antibody candidates in vivo! nature.com/articles/s4158…
Fixed! Nice response from @rahulvohra and @Superhuman team.
hey there! as you may have seen by now, we're changing this back 😄🙏
Anyone else attempting to reprogram over a decade of muscle memory with Superhuman changing the 'reply-all' keyboard shortcut from 'A' to 'enter' today?
Highly recommend for engineers/scientists looking to catalyze their own founder journey:
The world needs 10x more scientist-founders. 5050 helps scientists and engineers become great founders and start indispensable companies. Applications open! Startups are the best way to make a real impact with research, but where do you get started? How do you know if…
From a scientist at @ManifoldBio today who is integrating nanopore sequencing into our library protein engineering workflows: "We asked Oxford's product development people a few questions and they said no one has pushed their technology in that way before."
Brain delivery BBB-penetrating antibodies can dramatically improve protein drugs for the CNS, but we lack good shuttles especially for the newer BBB-transport targets. Manifold Bio combines ML with an in-vivo screen to identify new designs for next-gen brain shuttles
I just had an email attachment of phage genomes blocked because the scanner found a virus. I'm in awe
If you're at PEGS Boston right now, come check out @ManifoldBio's poster being presented by one of our talented scientists @alexcampreis
Come check out @ManifoldBio’s use of protein multiplexing to discover brain shuttles with optimal VIVO properties for delivering payloads for neuro disease!
Big presentation from @ManifoldBio's Co-founder/CSO @PierceOgdenJ this Wednesday at one of the major annual protein engineering conferences PEGS Boston.
Join us at the PEGS Summit in Boston this week! Manifold’s CSO and co-founder Pierce Ogden will share the latest on Manifold’s multiplexed in vivo protein design platform and our work on brain-shuttled biologics. Day 3 - May 15 at 3:30pm. 🧬#PEGSummit #PEGS2024 #Biotech
A sneak peek of what's coming...
Manifold Bio is thrilled to announce that we'll be presenting a poster at #AANAM! Swing by and catch Co-Founder @ShaneLofgren in action as he shares the latest updates on our brain shuttling work enabled by our in vivo multiplexing platform . #AANmember #AANmember #Neuroscience