James Good
@drjamesgood
GI oncologist | Immunotherapy & adaptive radiotherapy fan | Husband, father | Englishman | Civilisation enjoyer
🧠 This chart popped up in my feed via @balajis It shows the exponential growth in human brain size and complexity over evolutionary time. It got me thinking about oncology. Cancer medicine now sits at the convergence of: 🧬 Biological complexity 🙏 Moral gravity 🚀…

No role for mediastinal LN dissection in clinical stage T1N0M0 GGO-dominant invasive lung adeno, defined by consolidation-to-tumor ratio (CTR) ≤0.5 & maximum tumor diameter (including solid and GGO components) ≤3 cm. Zero positive hilar nodes in those that were resected!
Phase III Study of Mediastinal Lymph Node Dissection for Ground Glass Opacity–Dominant Lung Adenocarcinoma. Read the full article. brnw.ch/21wUqiZ
🚨ACCORD Trial🚨 Resected Extrahepatic CCA or Gallbladder CA 🔍Randomized Adjuvant CRT + Camrelizumab vs Observation 🔥Whopping improvement in OS and RFS with CRT + ICI with persistent separate at tail of the curve!!! tinyurl.com/64yc3uum @JAMAOnc
MR-guided SCRT delivered over 5 fractions in just 1 week is an effective option for frail or oligometastatic patients. Real-time imaging, daily plan adaptation & dose escalation = better precision, fewer side effects. Find out more here 👉🏽bit.ly/4o6Zf7A
Prof Sikora’s generation had: ✅ free tuition ✅ no 100k debt ✅ free accommodation ✅ final salary pensions ✅ clinical excellence awards ✅ family home at 3x salary ✅ 20-30% higher salary ✅ Job security ✅ Lower cost of living None of which is true for current Drs 2/3
Pancreatic cancer moves fast which is why early treatment is critical. At GenesisCare, our Rapid Access Pathway gets eligible patients with localised disease into treatment within 5 working days. Find out more here 👉🏽bit.ly/4kPdawd
Our newest CAPRI trial, called PREVENT, is a phase II/III RCT testing high dose palliative RT for NSCLC to dose of 35/5, with esophageal sparing. 🇨🇦 We hope this will improve survival and QOL. Congrats @goodmanC_MD for getting this off the ground! ⬇️⬇️⬇️
Thrilled to activate PREVENT! This phase II/III RCT builds on the success of @DrAlexLouie's PROACTIVE trial by randomizing patients requiring palliative thoracic RT 2:1 to high-dose esophageal-sparing vs. traditional palliation to a max dose of 30 Gy in 10 equivalent
The Force was with us today @UTSW_RadOnc! We treated our first HANSOLO patient using Ethos: Head And Neck radiotherapy with Simulation Omitted and setup and pLanning Online. Patient needed emergent radiotherapy to control bleeding but may receive definitive treatment later,…
I gave a speech today in an empty chamber. It’s about the need for a Christian restoration.
🎥 Curious how we're transforming gynae cancer care with MR-guided SABR? @eminowicz & Ebison Chinherende show how MR Linac tech is driving precision & adaptability in treatment. If you're a clinician wanting to drive innovation in cancer care, watch now👉🏿bit.ly/3TgJBs9
We're delighted to share our two posters from #BGCS2025 on MR-guided SABR for gynaecological cancers - a precise, non-invasive option for patients unsuitable for brachytherapy. 📥 Learn more & download: bit.ly/46z53jK
Incredible #RadOnc Grand Rounds @MGHCancerCenter by Dr. Jona Hattangadi-Gluth @JHGLab on oncofunctional balance in brain tumors—from connectomics to clinical trials. Loved the focus on neuroimaging biomarkers, cognitive-sparing therapies, and the future of precision radiation…
richard feynman's love letter to his late wife is the best thing you’ll read today.
STELLA: Self-Evolving LLM Agent for Biomedical Research 1.STELLA is a self-evolving biomedical AI agent that learns and improves through experience. Its architecture allows it to dynamically grow its reasoning skills and computational capabilities by integrating new tools and…
I learned this week that SABR-COMET patient #1 recently passed away, more than 12 years after enrollment, with no recurrence since his original SABR. We initially treated him for a left adrenal met. It’s an interesting story… ⬇️⬇️⬇️
While I'm here, I'll just point out that RCTs of SABR don't show that radiation leads to more metastases...if anything the relationship is going the other way. Here's the data from Dan Gomez's oligomets RCT...
🖼 The “Viral” Spread of Radiation The moment Wilhelm Conrad Roentgen published an X-ray of his wife's hand in 1895, the public was in a frenzy! Then, three years later as Marie Curie discovered radium, intrigue about radiation continued to spread. The Untitled (Side Show…
We're taking a big step towards medical superintelligence. AI models have aced multiple choice medical exams – but real patients don’t come with ABC answer options. Now MAI-DxO can solve some of the world’s toughest open-ended cases with higher accuracy and lower costs.