Chen Wang 王晨

My lab has postdoc openings in the following areas: 1) Structural biology and single molecule biophysics; 2) Developing novel genome editing methods; and 3) Protein and RNA engineering. Please share the info with your trainees, and RT please. 🙏 postdocs.yale.edu/yale-postdocto…

1/3 Excited to share our work published in @Nature! We uncover how phages inhibit CRISPR-Cas immunity via RNA anti-CRISPRs (𝗥𝗮𝗰𝗿𝘀)! nature.com/articles/s4158…

In January 2026, I will be joining Berkeley @UCBerkeley as an Assistant Professor in the Department of Chemical and Biomolecular Engineering, College of Chemistry @UCB_Chemistry, with exciting connections with world-class communities including the Lawrence Berkeley National…

New Preprint!! @alex_gonzadel accomplished a major feat on this one: ported retron recombineering, which we love so much in E. coli, into 14 new bacterial species via a massive collaborative effort involving 9 labs! biorxiv.org/content/10.110…

🌟We are hiring! Seeking a postdoc to use molecular dynamics and AI to understand how ion channels are regulated by membrane lipids🌟 Join us at @ourANU with amazing collaborators and great working conditions! Apply: tiny.cc/corry. Us: karri.anu.edu.au

Hot off the press from the RTI: Disassembly activates Retron-Septu for antiphage defense pubmed.ncbi.nlm.nih.gov/40504952/?utm_… #RNA #RNATherapeutics

We discovered a new immune signaling molecule: N7-cADPR N7-cADPR is produced by phage-stimulated TIR proteins. It activates a bacterial caspase, which then degrades essential proteins to curb infection Preprint: biorxiv.org/cgi/content/sh… Congrats @FrancoisRousset & @IlyaOsterman

Tricking phages with reverse transcription @IlyaOsterman summarized the beautiful discoveries from the labs of @SternbergLab and @zhangf, who showed how bacteria defend against phages by expressing a protein that is not really encoded in their DNA science.org/doi/10.1126/sc…

I am looking for a post-doc to work on our ⁦@MBIEsci⁩ project on #phages for #biocontrol #microbiology #genomics #genetics ⁦@microtago⁩ ⁦@otago⁩ pls repost otago.taleo.net/careersection/…

We’re #hiring! A #postdoc is available in Kobe lab to work on structure-guided inhibitor design of proteins involved in immune system. See job advertisement at uq.wd3.myworkdayjobs.com/en-US/uqcareer…. Apply by 13th August 2024 11:00 pm. #structuralbiology #drugdesign

Excited to share our findings on Tandem Kinase proteins, a new class of disease resistant proteins by directly binding to corresponding effectors. Feedback welcome!

Thrilled to share our latest work together with the labs of Yixiao Zhang and @Charles_D_Cox, featuring our own @Riottowow & @Sitong_hst published today in @Nature. Our part done at @ANU_RSB_BSB using supercomputing at @NCInews #mechanosensation #biophysics nature.com/articles/s4158…

Mechanism of the Hachiman immune system finally deciphered A beautiful study from the Doudna lab shows that Hachiman is a genome integrity sensor biorxiv.org/content/10.110… Congrats @doudna_lab and colleagues!

Exited to announce the publication of our work showing that activated type I Thoeris SIR2 effector ThsA forms helical filaments in @Nature. Thread below nature.com/articles/s4158…

AlphaFold-Multimer predicts cross-kingdom interactions at the plant-pathogen interface. nature.com/articles/s4146…

Are you a data-driven person who likes working with a diverse group of academics from atmospheric science through to microbiologists? Please consider applying for this Data Manager post (5YEARS!) @BIFoRUoB @unibirmingham

New day, new mechanism of bacterial anti-phage defense! In our latest preprint, we describe how bacteria conjugate ubiquitin-like proteins to interfere with phage assembly: biorxiv.org/content/10.110… Details below 👇

Proud to share our latest discovery: Bacteria conjugate ubiquitin-like proteins to interfere with phage assembly A new concept in antiphage immunity, and a mechanism for ISG15-like antiviral defnese in bacteria. Big congrats to talented @Jens_Hoer! A 🧵 biorxiv.org/content/10.110…