Katherine Aird
@airdlab
My lab studies the interplay between cancer metabolism and cell cycle dysregulation. Moving to The Wistar Institute in September!
Thrilled to share a new lab preprint spearheaded by superstar postdoc @ApoorvaUboveja in collaboration with @mzspectrum! We discovered something totally unexpected – aKG is important for histone acetylation! biorxiv.org/content/10.110…
If you are worried about the constitutional crisis, NIH/NSF funding, diversity issues, or anything else: CONTACT YOUR REPRESENTATIVES. For those in PA: Dave McCormick: 202 224 6324 (mccormick.senate.gov/share-your-o...) John Fetterman: 202 224 4254 (fetterman.senate.gov/contact/)
Thanks to the preprint club for this lovely review of our new work! Check out the updated preprint if you are interested in learning about noncanonical roles of CDKN2A, zinc, TAMs, and immunotherapy. biorxiv.org/content/10.110…
CDKN2Alow tumours mediate immunotherapy resistance by depriving macrophages of zinc bit.ly/4cK5Mjf
The House will soon vote on a continuing resolution to fund government programs through the end of fiscal year 2025 (FY25). Ask Congress to vote no on this proposed legislation that would disrupt research into new therapeutics for ovarian cancer: bit.ly/3Fdymgr.
Congress is voting on a bill that cuts cancer research funding at the DoD by more than 50%! This would be devastating to the Pancreatic Cancer Research Program. Join me in telling Congress to vote NO on cuts! p2a.co/nPxyvAu
Trump's illegal NIH cuts mean cancer researchers would be laid off, sick kids going without treatment, and more. These cuts would be DEVASTATING for lifesaving research. Some Republicans have said they agree—but they just blocked my amendment to reverse Trump's NIH cuts anyway.
To protect Pennsylvania's interests and the funding appropriated to us by Congress, I’m left with no choice but to pursue legal action to defend our Commonwealth.
Nearly every medicine we benefit from started with NIH-funded research. Early discovery work starts in academia. Immunotherapies? Gene therapy for rare diseases? Alzheimer’s and Parkinson’s medicines? Vaccines? Novel cancer treatments? Psychiatric medicines? You betcha. 1/
The National Institutes of Health (NIH) announced a new policy for indirect cost reimbursement for research grants that could threaten to have a devastating impact on cancer research in the country. Urge the President to keep cancer research a priority: bit.ly/3EInczH
Things I wish more people knew about doing science in the US (thread):
CFPB - closed USAID - closed Medicaid - under attack NIH cancer funding - frozen Department of Education - under attack But do you know who just got a NEW government contract for $38,858,978 literally today? SpaceX — owned by Elon Musk
98% of NIH grants that should have gone out this month, didn't. Despite court orders 'unfreezing' the funds, they are frozen. Biomedical research will grind to a halt. Clinical trials will end. All for no reason: the total impact on the US budget is miniscule
We live in an age of (NIH-funded) biomedical miracles Within your lifetime, prion disease was considered potentially impossible to cure. Now there's a promising path towards one science.org/doi/10.1126/sc…
Want to get new cancer drugs in the next ten or twenty years? Impressed by the power of glp-1 obesity drugs? Fund the NIH.
CDKN2ALow cancer cells outcompete macrophages for microenvironmental zinc to drive immunotherapy resistance biorxiv.org/content/10.110… #biorxiv_cancer