Andy Posbe

Pikobodies vs. Potato Blight 🥊🥔 NLR–Nanobody Fusions Take on P. infestans 💥 🎤 Talk: Thurs July 17th, 16:35 🧾 Poster P-64: Tues 15th, Session 2 Poster’s up on Zenodo if you’re into spoilers 👀📎 zenodo.org/records/158479… #2025ISMPMI #OpenMPMI🌿

New preprint: A conserved small RNA-generating gene cluster undergoes sequence diversification and contributes to plant immunity (2025) | tsl.ac.uk/publications/1…

Had an awesome time at ISMPMI and the honour to present some of our work! Greatful for the oppurtunity to meet new people, catch up with friends, and see and discuss some great science! If you want to learn more the poster is up online: zenodo.org/records/158817…

Can AI structural modelling distinguish between sensor and helper NLR immune receptors? Toghani et al. @amiralito_ @Tolga_Bzkrt @ryoheiterauchi @KamounLab @YuSugiharaY 📖 nph.onlinelibrary.wiley.com/doi/10.1111/np…

Undruggable ‘disordered’ proteins become druggable with new AI techniques from David Baker. @ScienceMagazine science.org/doi/10.1126/sc…

Great reunion of (part of) the PERU receptor team at #2025ISMPMI 🙌🥳 Joining forces to improve PRR-mediated immunity against Late Blight 🥔🌱🧬 @adnroide @VivianneTwit @Yerisf_TA @LishaZhang2 @amiralito_

#2025ISMPMI Want to know about transcriptional regulation driving pathogenicity in the blast fungus? Come to my poster (P-156) session today! From 13:30 to 15:15 🌾

#2025ISMPMI Excited to share insights from my postdoc work at @TheSainsburyLab on NLR diversity and evolution in Caryophyllales phylogenomics 🥗 Join me at poster no.65 😊🤩

🎉 Exciting news during #2025ISMPMI Our AlphaFold 3 sensor vs helper NLR paper is now published in @NewPhyt! Big thanks to the reviewers for their constructive feedback 🙏 📖 Check out the peer-reviewed version here 👇 🔗 nph.onlinelibrary.wiley.com/doi/10.1111/np… x.com/YuSugiharaY/st…

Thrilled to share an aspect of my PhD project on the discovery and characterisation of a novel group of 'phosphorylated' effectors deployed by the rice blast fungus during infection. With @talbotlabTSL @Frank_Menke @NeftalyCM @TheSainsburyLab #2025ISMPMI

🚨New @biorxivpreprint alert! We are thrilled to share our latest findings—building on our earlier work on suppressors of helper NLRs of NRC family—a Phytophthora infestans L-shaped effector captures resistosome assembly intermediates of tomato NRC3! biorxiv.org/content/10.110… 1/10

Check out this wonderful story from @JMadhuprakash and Ben Seager! An L-shaped effector suppresses NRC activation by blocking resistosome assembly half way through!

Proud of PERU #potato poster at the MPMI2025 meeting in Cologne! ⁦@Brabrara_⁩ ⁦@Yerisf_TA⁩

Up and ready! Find me at P-267 today for some molecular evolution and NLR biology! 🥬💻 You can also find the poster and preprint below 👇🏻 #2025ISMPMI

A plant pathogen effector blocks stepwise assembly of a helper NLR resistosome biorxiv.org/content/10.110… #biorxiv_plants

Thrilled to join #ISMPMI2025! 🌿🧬 Can AIphaFold 3 tell sensor vs helper NLRs? 🤖 📍 P-452 | Tue 15 Jul | 09:55-11:30 Can’t be there? Grab the poster on Zenodo 👉 doi.org/10.5281/zenodo… #OpenMPMI #OpenScience

Lots to celebrate today — from preprints and papers to fellowships (and a few more I’m surely forgetting)! 🎉👏 Huge congrats to all. Great to see teamwork and dedication paying off! 🥂

Looking forward to meeting friends and colleagues at #2025ISMPMI next week! Find me at P-267 >>> Session 1, Monday, 14th. In the meantime, you can check out my poster on Zenodo :) #openscience zenodo.org/records/158379…

Thrilled to share our latest @biorxivpreprint! This work started during my PhD and was finished together with @JMadhuprakash. We found a Phytophthora infestans L-shaped effector that bridges a host TOL protein to activated NLRs to suppress immunity! biorxiv.org/content/10.110… 1/15

Plz RT. We are looking for a postdoc to join our collborative project on AI-guided bioengineering of plant immune receptors @Tolga_Bzkrt and @JiorgosKourelis labs: jobs.ac.uk/job/DNV032/res…