Jave Bautista
@javebautista17
PhD student @talbotlabTSL and MSc graduate @TheSainsburyLab; rice, fungal pathogens and effectors || 🇵🇭 👨🔬🌾🧬🔬🦠🧫
Editor’s Pick! Pathogenic bacteria use Type 3 effectors to suppress host defenses. The cassava pathogen Xanthomonas phaseoli pv. manihotis (Xpm) causes severe disease, but its effector functions are not well understood. @dianagdlc et al. show that the Xpm effector XopAE…
Graduation day for two of @TheSainsburyLab #Proteomics team members. Congratulations @DraegerMarkus PhD and @Miicchae1 MSc. Double #ProudSupervisor
🎉 Exciting news during #2025ISMPMI Our AlphaFold 3 sensor vs helper NLR paper is now published in @NewPhyt! Big thanks to the reviewers for their constructive feedback 🙏 📖 Check out the peer-reviewed version here 👇 🔗 nph.onlinelibrary.wiley.com/doi/10.1111/np… x.com/YuSugiharaY/st…
Please check our latest paper on using @GoogleDeepMind AlphaFold 3 to study NLR immune receptors. Here we use AI-guided structural modelling to distinguish between sensor and helper NLRs! 👇🧵 (1/10) #EvoMPMI #NLRbiology #PlantPath #PlantSci doi.org/10.1101/2024.1…
Our paper is now online in Science Advances! Congrats @SaskiaHogenhout @JohnInnesCentre and all coauthors! science.org/doi/10.1126/sc…
#2025ISMPMI Excited to share insights from my postdoc work at @TheSainsburyLab on NLR diversity and evolution in Caryophyllales phylogenomics 🥗 Join me at poster no.65 😊🤩
Thrilled to share an aspect of my PhD project on the discovery and characterisation of a novel group of 'phosphorylated' effectors deployed by the rice blast fungus during infection. With @talbotlabTSL @Frank_Menke @NeftalyCM @TheSainsburyLab #2025ISMPMI

The Magnaporthe oryzae MAX effector AVR-Pia binds a novel group of rice HMA domain-containing proteins biorxiv.org/content/10.110… #biorxiv_plants
Here is @EuanCawston at his poster. #2025ISMPMI #proudsupervisor
Today at #2025ISMPMI I'll present poster P188 about our work with @talbotlabTSL infection-related development in Magnaporthe oryzae using #phosphoproteomics. @Euan-Cawston will present poster P-340 on work investigating feedback regulation in MAPK signalling in M.oryzae.
Early start traveling to #ISMPMI2025. @TheSainsburyLab #Proteomics group presenting posters P088 WenWang, P340 @EuanCawston, P188 @NeftalyCM, and P129 @markjavebautista, including collabs with @talbotlabtsl @jonathandgjones
Multipartite coevolution shapes plant apoplastic immunity against rice blast fungus biorxiv.org/content/10.110… #biorxiv_plants
Finally, the nucleus shrinks and releases its contents into the cytoplasm. The hypersensitive cell death concludes with the collapse of the tonoplast and plasma membrane systems.
Challenges to #wheat disease resistance and current global strategies @AnnualReviews doi.org/10.1146/annure…
SO excited to share that I’ve been awarded a grant from @osventuresllc to develop a genetic toolkit for flower design! Here was my 1-minute pitch. To everyone who’s supported my art over the years, thank you. So much to come 🌹✨
IN BRIEF: The fungus among us: Rice blast fungus blocks ROS production and starch breakdown to disrupt host resistance (Vicky Howe) doi.org/10.1093/plcell… @DrVickyHowe @ASPB #PlantSci
New Postdoc position (2yrs) available in our #EvoMPMI lab @JohnInnesCentre. Come and work with on harnessing the diversity of immune mechanisms to protect plants. jobs.jic.ac.uk/Details.asp?va…
Join us for another day at the #RoyalNorfolkShow to talk about what we do at @TheSainsburyLab !
We’re ready! And we have a LIVE reporter today 😆 #RoyalNorfolkShow2025
We are excited to share our new story with you! We show how losing a binding domain can flip an antimicrobial effector into a host immune suppressor, highlighting functional specialization across the saprotrophy–symbiosis spectrum. Read more: biorxiv.org/content/10.110…
Please check out the improved, and peer-reviewed version of our work now published on Plant cell 😀🥳🥳🥳 @talbotlabTSL @TheSainsburyLab academic.oup.com/plcell/article…