Alessandro Carrer

bioRxiv has a dedicated section for negative results. Use it. Share negative results. Your colleagues will appreciate it.

Excited to share our new preprint on @biorxivpreprint from our great team @EMBL! biorxiv.org/content/10.110… If the nucleolus is liquid-like, why does it often appear irregularly shaped in proliferating mammalian cells? What controls the nucleolar shape? #PhaseSeparation #Nucleolus

The source of dietary fat influences anti-tumour immunity in obese mice go.nature.com/4o2w4CJ

Thank you @ZouYilong and Charles David for this thoughtful commentary on our recent study connecting PCSK9 status with PDAC metastatic tropism

We are very excited to officially launch our single cell proteomics service!! Please, check out our website if you want to work with us! sidolilab.org/single-cell

Top!! Congratulations to @BenStanger01 for the lead

A special @jclinicalinvest series on #PancreaticCancer led by @BenStanger01 jci.org/articles/view/… jci.org/articles/view/… jci.org/articles/view/… jci.org/articles/view/… jci.org/articles/view/… Articles by @lauradelongwood @Muir_Lab @MaddipatiLab

🤯 in @CellCellPress An alternate receptor for adeno-associated viruses cell.com/cell/fulltext/… carboxypeptidase D [CPD] is an alternate AAV receptor- totally explains why AAV8 vectors are SO efficient at pancreatic exocrine cell transduction for CRISPR engineering.

50% OFF From One Cell: A Journey into Life's Origins and the Future of Medicine - through Aug 11! audiobooks.com/promotions/pro…

Proudly presenting Simon’s paper on asymmetric apportioning of old mitochondria biasing intestinal stem cells for the Paneth cell linage through aKG-dependent metabolism @NatMetabolism nature.com/articles/s4225… @helsinkiuni @HiLIFE_helsinki @SuomenAkatemia @MetaStem_Center

Absorption of water and nutrients within the human GI tract #TIC2025

Kudos to @AnnaPellattiero C Quirin @MagrinFederico, great collaborators S Moro A Mattarei @msturlese @ProfGavathiotis for our latest @ScienceAdvances paper science.org/doi/10.1126/sc…. Many years in the making but finally we have OPA1 inhibitors reverting cancer chemoresistance! 1/

Our #pancreatic #research community is growing! More labs are now affiliated to @ItalianPCC 💜🔬🧪🧫 Check them out here 👇🏻 i-pcc.org/news/welcome-t…

A comparison of mouse vs human tumor microenvironments shows a major difference. Mouse TMEs have more macrophages, while human TMEs have more T cells. Chemokine expression patterns are also different. Learn more: biorxiv.org/content/10.110…

CASSANDRA trial presented at #EPC2025 PAXG 🤜🏼🤛🏼FOLFIRINOX in resectable and borderline resectable PDAC 🏆PAXG prolongs Event Free Survival (16 vs 10.2 months) Amazing results from 🇮🇹

🚨New Article Alert from @NatureCancer ! 'Self-amplifying NRF2–EZH2 epigenetic loop converts KRAS-initiated progenitors to invasive pancreatic cancer' ✏️ By Michael Karin and colleagues 🔗 nature.com/articles/s4301…

Exciting findings from @StefanoCrippa6 team (presented by P.R.Camisa at @EurPancClub 2025) on the prospective identification of molecular and inflammatory markers to predict malignant evolution of IPMNs!!

Strongly recommend this study I heard at @EurPancClub 2025 @IEspositoPATH Epigenetic characterization (DNAme) of Mucinous cystic neoplasms of the pancreas and liver - The Journal of Pathology …thsocjournals.onlinelibrary.wiley.com/doi/full/10.10…

I am thrilled to share with the world a new preprint, spearheaded by the truly amazing Jose Reyes in partnership with @LoweLabMSKCC. Focused on the benign to malignant transition in PDAC, uncovering roles of plasticity, tissue remodeling and P53 -> biorxiv.org/content/10.110…

Recent news claimed scientists at UCLA had solved hair loss. Is this true? Let's dive in 🧵