WilsonLab
@WilsonLab2
Ribosomes & Translation Regulation; Antibiotics & Resistance Mechanisms; Structural Biology & Cryo-EM; University of Hamburg.
Our latest work on structures of translation initiation complexes trapped by natural product inhibitors kasugamycin, edeine and GE81112 is out in the Biorxiv…biorxiv.org/content/10.110…
Out Now! Structure of an archaeal ribosome reveals a divergent active site and hibernation factor bit.ly/3UhiSfp #Archaea #RibosomeStructure #PeptidylTransferase
Preprint from our collaboration with the labs of Gerry Wright and Shura Mankin @shuramankin identifying the first translation inhibitor binding to the E-site of the bacterial ribosome… researchsquare.com/article/rs-692…
New paper out in Mol Cell, where we show how N-myristolytransferases lipidate proteins on the translating ribosome! Continuing our successful collaboration with @DeuerlingLab & Shu-ou Shan @Caltech @snsf_ch @ETH_en cell.com/molecular-cell…
Thrilled that Patrick Cramer @mpgpresident was elected a Foreign Member @royalsociety, here at today's event! 🥳Congratulations also to Max Planck appointees Miltos Tsiantis @mpipz_cologne , elected as Fellow, Detlef Lohse & Claudia Felser @mpi_CPfS - science is international!😊
Mammalian tRNA acetylation determines translation efficiency and tRNA quality control doi.org/10.1038/s41467…
@DjuranovicLab is from today officially part of @BrownUniversity and Brown RNA center. We will have our new website soon. rna.brown.edu
Time-resolved cryo-electron microscopy can resolve protein motion on millisecond or even microsecond timescales, but the need for highly specialized tools and skills limits the method’s reach nature.com/articles/d4158…
With our RTI colleagues Xiaobin Ling and @WenwenFang2, we report cryo-EM structures of enigmatic bacterial RNA nanocages made of long-noncoding ROOL RNAs. Octamers are held by "A-minor staples" and other interactions. Congrats Xiaobin, Dima et al! nature.com/articles/s4158…
Activation of Retron-Septu for antiphage defense. Congrats @futianmin and all co-authors! science.org/doi/full/10.11…
Doudna super computer :)
DOE Announces New Supercomputer Powered by Dell and NVIDIA to Speed Scientific Discovery nersc.gov/news-and-event…
Designing New Chimeric Proline-Rich Antimicrobial Peptides to Enhance Efficacy Toward the ESKAPE+E: Beyond Sequence Extension mdpi.com/2218-273X/15/6…
Congratulations! The #ShawPrize in Life Science & Medicine 2025 is awarded to Wolfgang Baumeister for his pioneering development & use of cryo-ET. ❕shawprize.org/laureates/2025… @ShawPrize #CryoEM #cryoET #Award
Promoting ribosomal incorporation of backbone-modifying nonproteinogenic amino acids into nascent peptides by ATP-binding cassette family-F proteins and EF-P academic.oup.com/nar/article/53…
New structure of protist ribosome using RAPPL. biorxiv.org/content/10.110…
Die Uni Hamburg feiert! 🎉 Rund 200 Mitglieder der Universität haben heute die Bekanntgabe der ab Januar 2026 geförderten vier Exzellenzcluster im Audimax verfolgt. Wir zeigen die schönsten Fotos! 📸
Großartiger Erfolg! 👏 Die Uni Hamburg hat im Rahmen der Exzellenzstrategie den Zuschlag für vier Exzellenzcluster erhalten. Damit werden die bestehenden Exzellenzcluster ab 2026 für sieben weitere Jahre gefördert. uhh.de/f1iz0 (1/2)
Congrats! Professor Hiroaki Suga wins the 2nd Kobe Prize Grand Award | The University of Tokyo u-tokyo.ac.jp/focus/en/artic…
In our newly published study we show that the proline-rich antimicrobial peptide (PrAMP) Bac5 has a distinct mode of interaction with the ribosome compared to other PrAMPs…academic.oup.com/nar/article/53…
Some of the ribosomes purified using RAPPL and Cryo-EM structures solved in last couple of months . 2 bacterial and 2 eukaryotic in this case (1/2) biorxiv.org/content/10.110…
We are recruiting 🤩🤩🤩!!! If you are looking to establish your lab in a multidisciplinary institute with state-of-the-art facilities, horizontal structure and diverse faculty, all in a near-paradisiac city in the south-west of France, you have 6 weeks left to apply🤓!!!