Kozo Tomita Lab: RNA Biology

We are pleased to share our paper "Cryo-EM structure of human TUT1:U6 snRNA complex" published in Nucleic Acids Res. academic.oup.com/nar/article-lo…

A resource of RNA-binding protein motifs across eukaryotes reveals evolutionary dynamics and gene-regulatory function: nature.com/articles/s4158…

Had a great scientific time at RNA Tokyo @ IQB UTokyo with Prof. Phillip Zamore and RNA PIs from the Tokyo area. Big thanks to Prof. Yuki Tomari for organizing! Great discussions—and a fun evening at Hantei after the seminar.

Our study where we develop EvoBind2: Design of linear and cyclic peptide binders from protein sequence information is now published! nature.com/articles/s4200…

Today in the journal Science: BioEmu from Microsoft Research AI for Science. This generative deep learning method emulates protein equilibrium ensembles – key for understanding protein function at scale. msft.it/6010S7T8n

The eukaryotic tRNA chaperone La impacts tRNA modification levels (queuosine and others). Interesting because in procaryotes, tRNA modif enzymes themselves are thought to be chaperones. In both cases, there seems to be a link between modif and chaperones. academic.oup.com/nar/article/53…

We attended the 26th Annual meeting of RNA society of Japan in Sendai. Wondetful meeting as always and thank you organizers! A phD student and a postdoc from my lab presented their research.

Mammalian tRNA acetylation determines translation efficiency and tRNA quality control doi.org/10.1038/s41467…

Thank you Prof. Rujuan Liu for hosting and inviting me to the seminar at SLST, ShanghaiTech. It was a fruitful and enjoyable visit — great to meet and discuss with faculties and students!

New online! Structure of fungal tRNA ligase Trl1 with RNA reveals conserved substrate-binding principles bit.ly/3T4Zr9d

Arrived at Shanghai for seminar at ShanghaiTech tomorrow. Feel that Shanghai is really an enetgetic city!

With our RTI colleagues Xiaobin Ling and @WenwenFang2, we report cryo-EM structures of enigmatic bacterial RNA nanocages made of long-noncoding ROOL RNAs. Octamers are held by "A-minor staples" and other interactions. Congrats Xiaobin, Dima et al! nature.com/articles/s4158…

#ResultatScientifique🔎| Comment les plantes protègent l’ADN de leurs mitochondries 🤝@CNRS @CNRS_Alsace @cnrs_ibmp ✍️ José Manuel Gualberto et Frédérique Weber-Lotfi 📕 @ThePlantCell | academic.oup.com/plcell/article… insb.cnrs.fr/fr/cnrsinfo/co…

Visited Osaka for a research grant report session and stopped by Osaka University. Taro Okamoto’s Tower of the Sun, the symbol of　Osaka Expo ’70, was far larger and more striking than I had imagined (as alwasys)...

A programmable RNA acetylation system using dCas13-eNAT10 is developed to install N4-acetylcytidine on target RNAs in cells and in vivo, enabling functional studies of RNA acetylation nature.com/articles/s4158…

Application for the CBMS Entrance Examination Schedule-A (2026) begins tomorrow. Application Period: Thursday, June 5 to Wednesday, June 11, 2025, 11:00 PM (JST) Online Application Site: e-apply.jp/ds/gsfs/

CBMS Entrance Examination Schedule A, AY2026 Application Period: From Thu., June 5 to Wed., June 11, 2025, 11:00 PM (JST) Online Application site: e-apply.jp/ds/gsfs/ Admission details: cbms.k.u-tokyo.ac.jp/en/admission/a…

The previous photo of Dr. Chujo had the face partially cut off, so here's a better one.

It was a pleasure to have RNA biology seminar, share scientific time with Dr. Saito (NIG), Dr. Wei (Tohoku Uni), Dr. Chujo (@RNAbiker), and Dr. Rujuan Liu (ShanghaiTech Uni). Thank you all — and also Nono and Tom(@SuzukiRNALab) — for the great conversations & a fun time!

Congrats！ Professor Hiroaki Suga wins the 2nd Kobe Prize Grand Award | The University of Tokyo u-tokyo.ac.jp/focus/en/artic…

tRNA binding to Kti12 is crucial for wobble uridine modification by Elongator academic.oup.com/nar/article/53…