Sergej Djuranovic
@DjuranovicLab
Biochemistry, Genetics and RNA biology lab at Brown University RNA Center.
Our collaboration with @TonyMustoe lab is out today. MPRA libraries and possible cryptic splicing in MPRA reporters, or reporters in general. The additional novelty here is that such events are controlled or influenced by U-rich motifs. Soon more on this topic.…
First RAPPL ribosome isolation at the new lab space at Brown University. Purification from a small culture of parasitic Eukaryote. Soon out... biorxiv.org/content/10.110…
@DjuranovicLab is from today officially part of @BrownUniversity and Brown RNA center. We will have our new website soon. rna.brown.edu
New structure of protist ribosome using RAPPL. biorxiv.org/content/10.110…
Another great collaboration with Topisirovic Lab at McGill Universoty came out today. This is also use of our first patent. In @elife: Mitochondrial ETF insufficiency drives neoplastic growth by selectively optimizing cancer bioenergetics doi.org/10.7554/eLife.…
Last month @uspto issued yet another patent for @slavicaPD @DjuranovicLab and Jessey Erath for use of polybasic peptide or non-peptide moieties against malaria parasites. More soon...
This was a fun collaboration with @maxim_artyomov lab on how itaconate inhibits the active site of a peroxiredoxin enzyme. Thanks Maxim for including us in this. nature.com/articles/s4225…
Ready for the next RNA session in @ASBMB meeting. We start soon...
Our house is on the market from April 4th. redkeystlouis.com/p/1196-Laven-D…
Ribosome data collected from a new and precious sample of 10,000,000 cells from a strange organism. All done using RAPPL, more soon... biorxiv.org/content/10.110…
3 years after terrible loss (two -80C freezers and back-ups) of almost all of our collection of regular and mutant human, Drosophila, E. Coli and Plasmodium cells, we are still not finished with insurance. I should point out that this was a valuable collection of mutant cell…
One of the best single step purification preparations of protozoan ribosomes I've ever seen. Combination of RAPPL (biorxiv.org/content/10.110…) and new technique. More at rna.ucsc.edu/rnacenter/ribo…
Registration is open for the triennial Ribosome Meeting which will be held June 22-June 27, 2025 in Asilomar Conference Grounds, Pacific Grove California. Come and join us... rna.ucsc.edu/rnacenter/ribo…