Ahmed Ibrahim
@TheIbrahimLab
Assistant Professor, @SmidtHeart Podcast host to Saturday Morning Lab Apple: https://t.co/05I2HNPMqx Spotify: https://t.co/HnXRU8eLF Views are my own.
Interested in the raw experiences and rich perspectives of everyday PhDs? Check out my new podcast! Weekly episodes starting January 11th! podbean.com/ep/pb-y45nj-17…
Added to my summer reading list!
First copies of my book are here!! As a new faculty member, I realized that in addition to my research job, I also had a leadership job…and I wasn’t prepared for that. This book is the guide I wish I’d had then, with the goal of helping others now. jenheemstra.com/book
This work developed a structure model for the lncRNA SChLAP1, identified protein binding regions, and uncovered an unexpected role for retroviral insertions in forming an RNA conformational landscape. bit.ly/440bLhb
On this episode of Campfire Confessions, how cleaning up a minor car oil spill led to crashing a semi truck into a parking structure and a pleasant surprise this week in lab. podbean.com/eas/pb-yzivx-1…
Today’s #JournalClub featured Adarsh on new #AI-driven #DNA functional predictions (version 1.0), Hiro discussing oral #mRNA delivery to the gut (long run, short slide), @ThassioMesquita on the role of vagal tone in #HFpEF (unexpected role of #Tcells). Great presentations!
Despite treatments for multiple sclerosis, halting progression remains an unmet need. Charles L. Howe & team @MayoClinic discover inhibition of the pentose phosphate pathway in autoimmune CD8+ T cells reduces their neurotoxic effects in demyelinating disease models:…
TRAF6 regulates ubiquitination-independent TDP-43 condensation and related neurodegeneration: nature.com/articles/s4138…
On the third episode of Campfire Confessions, I share the story of a professor who delivered his conference talk to an enthusiastic audience of one! podbean.com/eas/pb-jynap-1…
Stellar job by my team today showcasing our work at @marbanlab Elevator Pitch Day! @AleCiulloPhD @soussi_salwa @DianaKitka97344 @kara_tsi
I'm such a fan of this sort of inter-taxa translational EV research. @MarbanLab conceived the same several years ago with the A1 cells of the regenerating limb of newts: nature.com/articles/s4159…
Extracellular vesicles from antler blastema progenitor cells (distinct population of skeletal mesenchymal stem cells found in regenerating deer antlers) reverse bone loss and mitigate aging-related phenotypes in mice and macaques @NatureAging nature.com/articles/s4358…
Parsing the STING in pulmonary hypertension— @ajbryantlab & team @UF report on opposing roles for STING in PH—a paradigm shifting mechanism suggesting we refocus on treatments that target cell-specific inflammatory activation: insight.jci.org/articles/view/…
Engineered exosomes show promise for treating chorioamnionitis by targeting immune cells and reducing inflammation in a primate model, offering new hope for women's health. exosome-rna.com/ilias-biologic…
Data suggest that the NLRP3 inflammasome engages an additional innate immune lytic cell death pathway, PANoptosis, for cell death beyond the early timepoints of innate immune responses, which may lead to new therapeutic targets. Learn more: ow.ly/ZkJy50WlNT1.
Super excited to share our recent publication in PNAS by Rui Zhang et al. describing how using CRISPR to remove pH sensitivity of NCX1 helps maintain its function during acidosis, which is cardioprotective during ischemia/reperfusion. pnas.org/doi/10.1073/pn…
On this episode of Campfire Confessions, Lars finally lands a job in a high-profile lab but faces a tough decision when a late night experiment goes completely wrong. podbean.com/eas/pb-e7ipk-1…
My brilliant postdoc, @DianaKitka97344 presenting the results of her AI campus team project. Here she demonstrates how machine learning can help speciate breast cancer subtypes @CedarsSinai #artificalintelligence #cancer #WomenInSTEM
Yesterday, my team and I presented our ML project on cancer subtype classification using the TCGA dataset as the part of @CedarsSinai AI campus project. Grateful for the past 4 months of learning and building! 💻🧬 #MachineLearning #TCGA #Cancer #datascience
Imaging of macrophage accumulation in solid tumors with ultrasound @NatureComms nature.com/articles/s4146…
We’re proud to share that @SmidtHeart #CardiacSurgery team has earned the highest 3-star rating from the @STS_CTsurgery — placing us among the nation’s best in heart surgery outcomes. “This new rating is testament to our program’s quality & safety record across the entire…
mRNA 3′UTRs chaperone intrinsically disordered regions to control protein activity biorxiv.org/content/10.110…
Episode 1 of Campfire Confessions is up! podbean.com/ew/pb-exv2h-18…