Shoutang WANG
@ShoutangW
Assistant Professor @HKUSBMS | study neuroimmunology & neuroinflammation | Marco Colonna alum @TheColonnaLab | #microglia #immunotherapy
OBS SPEAKER HIGHLIGHT Feeding Tolerance: The Role of RORγt⁺ Tolerogenic DCs in Shaping Gut Immunity 🗣️ Patrick Fernandes-Rodrigues @TheColonnaLab @WUSTLmed 📆 Thu, June 12, 11 pm ET 👉 Registration: us02web.zoom.us/meeting/regist…
🔬 OBS Seminar Feeding Tolerance: The Role of RORγt⁺ Tolerogenic DCs in Shaping Gut Immunity 🗣️ Lihui Fu @nyuniversity 🗣️ Patrick Fernandes-Rodrigues @TheColonnaLab @wusm_pathology @WUSTLmed 🧑🏫 @Javier_Oroz20 🗓️ Thu, June 12th, 11 pm ET 👇 us02web.zoom.us/meeting/regist…
🗣️ Patrick Fernandes-Rodrigues talk is now on Youtube! @TheColonnaLab @WUSTLmed 👉 Rorγt-positive dendritic cells are required for the induction of peripheral regulatory T cells in response to oral antigens youtube.com/watch?v=KNnJRU…
Check out Research Briefing for our recent paper in Nature Immunology @DuSiling nature.com/articles/s4159…
Mutations in the human CSF1R gene impact microglia’s maintenance of brain white matter integrity @NatImmunol @TheColonnaLab @DuSiling nature.com/articles/s4159… nature.com/articles/s4159…
Mutations in the human CSF1R gene impact microglia’s maintenance of brain white matter integrity nature.com/articles/s4159…
🧵1/ Excited to share my first publication from the @ColonnaLab in @NatImmunol! We investigated how mutations in the human CSF1R gene disrupt microglia and impair white matter integrity in a rare but devastating neurodegeneration called ALSP. nature.com/articles/s4159…
Our new study by @DuSiling reveals how CSF1R mutations in adult-onset leukoencephalopathy with axonal spheroids and pigmented glia (ALSP) disrupt glial homeostasis. Key roles for oligodendrocytes, astrocytes & STAT3 signaling. nature.com/articles/s4159…
Zhangying Cai, Shoutang Wang, Marco Colonna et al. show that Loss of ATG7 in #microglia impairs UPR, triggers #ferroptosis, and weakens amyloid pathology control. hubs.la/Q03pZLRg0 📘 In #Neuroimmunology & #Neurodegeneration 2025: hubs.la/Q03pZMWk0
Big shoutout to Brown’s group: IRF8-dependent TC are essential for inducing food-specific pTregs & establishing oral tolerance! In line with recent work from Mucida’s, Littman’s, Gardner’s, and our group highlighting the role of RORγt⁺ APC in this process.rb.gy/rej77q
As RORγt⁺ APC gain attention for their tolerogenic roles, Schraml’s group also highlights their inflammatory potential. Key questions remain: How are RORγt⁺ APC specified? Are eTAC and RORγt⁺ DC distinct or the same? What dictates tolerance vs. inflammation? Fast-moving field!
Find the referenced papers below: Brown: rb.gy/rej77q Mucida: rb.gy/1ulzqt Littman: rb.gy/9v8ke8 Gardner: shorturl.at/vTk7k Schraml: rb.gy/yhw499 Colonna: rb.gy/w50y70
The brain & immune system are more connected than ever imagined. In this issue of @ImmunityCP, 9 articles explore major advances & future directions in neuroimmunology. Take a look! hubs.li/Q03lzQ3H0
Congratulations to physicist Carl Bender of @washuartsci and immunologist Marco Colonna @washumedicine, who have been elected to the @americanacad for their pioneering work in quantum theory and immune pathways in Alzheimer’s. bit.ly/42SK87N
Congratulations, Marco @TheColonnaLab! Well deserved!
Congratulations to physicist Carl Bender of @washuartsci and immunologist Marco Colonna @washumedicine, who have been elected to the @americanacad for their pioneering work in quantum theory and immune pathways in Alzheimer’s. bit.ly/42SK87N
Interdisciplinary immunologists at all levels WANTED! Faculty recruitment at Institute for Immunology, Tsinghua University, Beijing. PLEASE SPREAD THE WORD!
Newly Discovered PNS Microglia Found to Regulate Neuron Size, by @hanjie_li and his lab. 👍
Proud to share our latest @CellCellPress paper. We present a novel immune population termed PNS microglia that regulate neuronal soma size throughout evolution. cell.com/cell/abstract/… #Microglia#PNS#NeuronalSomaSize#Macrophage#BodySize#Neuroimmunology#Evolution (1/8)
Now online! Rorγt-positive dendritic cells are required for the induction of peripheral regulatory T cells in response to oral antigens dlvr.it/TK0JNj
Rorγt-positive dendritic cells are required for the induction of peripheral regulatory T cells in response to oral antigens @CellCellPress @PatFernRod @TongWu99 @TheColonnaLab cell.com/cell/fulltext/… Huge congrats to my dear friend Patrick🥇🍻🎉
Excited to share that our work by @PatFernRod and @TongWu99 is published in Cell: RORγt+ DCs are required to induce oral tolerance. Their absence reduces pTregs and impairs oral tolerance to dietary antigens. Read more: authors.elsevier.com/sd/article/S00…