Siling Du
@DuSiling
Neuroimmu-enthusiast🧐GR5 IMM student in the Kipnis lab & Colonna lab at WUSTL| Interested in brain macrophages & neurodegeneration| Re-tweet to learn
Mast cells regulate the brain-dura interface and CSF dynamics @CellCellPress cell.com/cell/fulltext/…
Excited to share this new work from our lab, led by an exceptional graduate student, Tornike Mamuladze (@tornikemamu), on the role of meningeal mast cells in regulation of brain/dura access points, with implications to CSF flow dynamics and meningitis || authors.elsevier.com/sd/article/S00…
#aging #immune_aging NEW PREPRINT FROM Artyomov&Randolph labs: How mouse age-associated GZMK+ CD8 Taa cells develop and what are correct surface markers for them biorxiv.org/content/10.110… Among other things we - Using OT1-Rag2ko mice explicitly show the TCR dependence and yet…
Proud to share @niseto’s (new PI @TheCrick) paper: As a postdoc (@CSHL/@HopkinsMedicine), he found #NETs in necrotic tumors—I shrugged. But he looked closer: NETs block tumor vessel perfusion, causing necrosis, hypoxia, EMT & #Metastasis. nature.com/articles/s4158… @JHU_BDP @Nature
Using newly developed mouse models and a microglia replacement strategy, researchers in Science show that bone marrow transplantation could be used as an effective therapy for ALSP, a rare and fatal neurodegenerative disease. 📄: scim.ag/4kW4jsR #SciencePerspective:…
Replacing microglia to treat a brain disease | Science science.org/doi/10.1126/sc…
Check out Research Briefing for our recent paper in Nature Immunology @DuSiling nature.com/articles/s4159…