Franziska Sendker

Excited to share our latest work on the structure and mechanism of the ancient sodium-pumping Rnf complex, now out in @NatureComms nature.com/articles/s4146…

Man, protein crystallography is so fun whenever it is not the worst thing in the world 🥹

New paper from the lab from @SriramGarg. We introduce a general substitution matrix for structural phylogenetics. I think this is a big deal, so read on below if you think deep history is important. academic.oup.com/mbe/advance-ar…

Zero-shot design of drug-binding proteins via neural selection-expansion 1. This study introduces a powerful method for the zero-shot design of small-molecule binding proteins using neural networks. The approach combines two reciprocal neural networks, LASErMPNN and…

Really excited to work on a new project!!✨ Must not tell too much about it though…

Glad to see my main PhD project finally out @NatureMicrobiol nature.com/articles/s4156… We show for the first time that a synthetic and engineered pathway can indeed exceed nature at one-carbon fixation.

Excited to share this story now in @NatureComms where we investigate the molecular mechanisms behind the evolution of enhanced metabolic "addiction" between microbial partners in a synthetic community. rdcu.be/dRIE5 Many thanks to @sourjik for an amazing time in Marburg

Excited to announce our new paper on designing allosterically regulated protein assemblies from scratch, now published in @Nature! This collaborative effort included key contributions from @FloPraetorius, Abbas Idris, @AnnikaPhilomin, @cweidle1 and others! nature.com/articles/s4158…