Sarah Mundt
@SarahMundt5
Group leader Neuroimmunology lab @uzh_en
Phew!Just wrapped a great discussion with @viogogoleva & @BecherLab on MPs in neuroinflammation @TrendsImmuno and now we have the first functional evidence🚨of MdCs as key drivers of oxidative tissue damage (also first study from the Mundtlab led by @Juanvillarv) Checkitout👇
Check out our most recent work resolving a longstanding controversy: which phagocyte subset drives oxidative damage in neuroinflammation? Thank you for the support and the mentoring @SarahMundt5. Thanks to Mundtlab, @BecherLab and all coauthors! Link: biorxiv.org/content/10.110…
Check out our new study @SciImmunology, identifying a distinct molecular signature of treatment-refractory psoriatic arthritis patients🧬 It was an exciting and fun journey with Reut Tzemach, Chamutal Gur, Eyal David, @ShuangYinWang @IdoAmitLab team
Excited to share our study in @SciImmunology dissecting the immune landscape of psoriatic arthritis (PsA)—with a new finding: immunoproteasome overactivity drives treatment resistance🧵 Led by Reut Tzemach,Chamutal Gur,@TgSanPhan,Eyal David & team. (1/11) science.org/doi/10.1126/sc…
Our study on glioblastoma-associated immunoregulatory astrocytes is out in @Nature today by @CamiloFaustAkl! We identified GBM-derived IL-11 as a regulator of TRAIL+ astrocytes, which limit anti-tumor T cell responses via apoptosis. nature.com/articles/s4158…
Passionate about #immunology? Join my lab to study #autoreactive #Tcells in #neurological disorders. 🔬Lab Manager 🔬Lab Technician 🔬Postdocs @SanRaffaeleMI @MyUniSR @y_efis @SiicaI @syis_ecr linkedin.com/posts/daniela-…
Took some time and some very talented and very persevering researchers, but now our new insights on IL-12 in AD are published 🥳 Thank you all for this amazing journey 👏
Online now!✨RESEARCH: Schneeberger, Kim, Geesdorf et al tease IL-12 and IL-23 signaling apart to define a role for oligodendroglial and neuronal IL-12 signaling in neuroimmune crosstalk in Alzheimer’s disease nature.com/articles/s4358… rdcu.be/edpcb
Are you an immunologist interested in spatially-resolved single cell technologies and generative modeling but dont know where to start? Check out our @EurJImmunol review with Avital, Hosna, Robert Zeiser, @IdoAmitLab, @YosefLab & @WertheimerT onlinelibrary.wiley.com/doi/10.1002/ej…
Happy to share our recent work led by postdoc @DanCorral showing that the maternal adapative immune system promotes optimal lactogenesis. cell.com/cell/abstract/…
We are hiring (2 positions) one Postdoctoral fellow and one Clinician-Scientist (all genders) in neuroimmunological research | Universitätsklinikum Hamburg-Eppendorf uke.jobs/index.php?ac=j… uke.jobs/index.php?ac=j…
Excited to see our story now out in @NatureNeuro Many thanks to Sebastian @Ellorebo @MargheritaZamb2 @SarahMundt5 @FrisenJonas and all the other contributors! nature.com/articles/s4159…
Brain macrophages in vascular health and dysfunction dlvr.it/TH2VJf #immunology
Excited to share our new paper in @JExpMed 🎉 We show that NK cells use autocrine TGF-β1 signalling to establish tissue residency, form a highly cytotoxic subset, and protect the tissue against viral persistence. rupress.org/jem/article/22…
Another @preprintclub Journal Club by Zi Yan Chen & @nkg2d1 @ImmunologyUofT discusses @biorxivpreprint by @VillarVesga et al. @BecherLab @SarahMundt5 showing that monocyte-derived cells in CNS produce mitochondrial ROS to promote neuroinflammation bit.ly/495E7HP
Pathogenic role of mitochondrial ROS in neuroinflammation with monocyte-derived cells rather than microglia as the primary driver of ROS-mediated neuropathology @VillarVesga @SarahMundt5 papers.ssrn.com/sol3/papers.cf…
We are recruiting! A PhD position is available @LabLeibundgut on Malassezia-host interactions. We are looking for highly motivated, creative and dedicated team player. Please apply before 1st November via our PhD program @MimZurich at mim.ethz.ch/application/ap…
The Neuroimmunology – II special issue, showcases current research in this discipline, emphasizing the reciprocal interplay between our immune and nervous systems. Take a look. hubs.li/Q02SW6mJ0
Hub#1 is back TODAY 🥳 we will start with Arthur Mortha @nkg2d1 from @ImmunologyUofT , who will present a #preprint by @BecherLab and @SarahMundt5 labs about the role of monocyte-derived cells in oxidative tissue damage in neuroinflammation 🤯💥🩹 👇 biorxiv.org/content/10.110…
35 most useful tools for PhD students and researchers. Literature Review 1. @LitmapsApp 2. @R_Discovery 3. @Scite 4. @ConnectedPapers 5. @ResearchPal_AI 6. Journal Finder Paper Writing 1. @teampaperpal 2. @thetrinkaai 3. @Grammarly 4. @scispace_ 5. @overleaf 6.…
Result of a rewarding experience to summarize our knowledge on meningeal biology with established experts in the field below. I hope this provides inspiration for further research studies aiming to find the truth. rdcu.be/dVigd
Notch signaling regulates macrophage-mediated inflammation in metaboli... sciencedirect.com/science/articl… Very happy to share our latest work on the spatio-temporal regulation of macrophage differentiation in MASH!
Neuroimmunologists fans, we're looking for a post-doc to join our team :) !!